This review describes the family of intrinsically disordered proteins, members of which fail to
form rigid 3-D structures under physiological conditions, either along their entire lengths or …

Regulation, recognition and cell signaling involve the coordinated actions of many players.
To achieve this coordination, each participant must have a valid identification (ID) that is …

The recent advances in the prediction of intrinsically disordered proteins and the use of
protein disorder prediction in the fields of molecular biology and bioinformatics are reviewed …

The existence and functioning of intrinsically disordered proteins (IDPs) challenge the
classical structure-function paradigm that equates function with a well-defined 3D structure …

Intrinsically disordered proteins (IDPs) defy the structure–function paradigm as they fulfill
essential biological functions while lacking well‐defined secondary and tertiary structures …

Hypertrophic cardiomyopathy (HCM) is one of the most common causes of sudden cardiac
death in young adults and is a familial disease in at least 60% of cases. Causative mutations …

Regulation, recognition and cell signaling involve the coordinated actions of many players.
Signaling scaffolds, with their ability to bring together proteins belonging to common and/or …

Contrarily to the general believe, many biologically active proteins lack stable tertiary and/or
secondary structure under physiological conditions in vitro. These intrinsically disordered …

To cause disease in maize, the biotrophic fungus Ustilago maydis secretes a large arsenal
of effector proteins. Here, we functionally characterize the repetitive effector Rsp3 (r epetitive …

Neurodegenerative diseases constitute a set of pathological conditions originating from the
slow, irreversible and systemic cell loss within the various regions of the brain and/or the …