A Systematic Review of the Molecular Mechanisms Involved in the Association Between PCOS and Endometrial and Ovarian Cancers

M Zanjirband, MH Nasr‐Esfahani… - Journal of cellular …, 2024 - Wiley Online Library
Polycystic ovary syndrome (PCOS), a major cause of female infertility, affects 4%–20% of
reproductive‐age women. Metabolic and hormonal alterations are key features of PCOS …

[HTML][HTML] Towards the early detection of ductal carcinoma (a common type of breast cancer) using biomarkers linked to the PPAR (γ) signaling pathway

G Sultan, S Zubair, IA Tayubi, HU Dahms… - Bioinformation, 2019 - ncbi.nlm.nih.gov
Breast cancer is a leading cause of morbidity and mortality among women comprising about
12% females worldwide. The underlying alteration in the gene expression, molecular …

[HTML][HTML] Identification of marker genes in Alzheimer's disease using a machine-learning model

IH Madar, G Sultan, IA Tayubi, AN Hasan, B Pahi… - …, 2021 - ncbi.nlm.nih.gov
Alzheimer's Disease (AD) is one of the most common causes of dementia, mostly affecting
the elderly population. Currently, there is no proper diagnostic tool or method available for …

The endometrial transcriptome of metabolic and inflammatory pathways during the window of implantation is deranged in infertile obese polycystic ovarian syndrome …

V Salamun, M Rizzo, L Lovrecic, K Hocevar… - Metabolic Syndrome …, 2022 - liebertpub.com
Introduction and Aim: Obese women with polycystic ovarian syndrome (PCOS) have a
reduced rate of spontaneous conception even when their cycles are ovulatory. Endometrial …

[HTML][HTML] Identification of the core ontologies and signature genes of polycystic ovary syndrome (PCOS): A bioinformatics analysis

MR Islam, ML Ahmed, BK Paul, T Bhuiyan… - Informatics in Medicine …, 2020 - Elsevier
Worldwide polycystic ovary syndrome (PCOS) is one of the most common hormonal
disorders in women of reproductive age. However, there is a lack of genetic study of the …

Obesity does not alter endometrial gene expression in women with endometriosis

SJ Holdsworth-Carson, J Chung, C Sloggett… - Reproductive …, 2020 - Elsevier
Research question Does obesity affect endometrial gene expression in women with
endometriosis, specifically women with stage I disease? Design Differential gene …

Candidate genes for infertility: an in-silico study based on cytogenetic analysis

JS Sahota, B Sharma, K Guleria, V Sambyal - BMC Medical Genomics, 2022 - Springer
Background The cause of infertility remains unclear in a significant proportion of
reproductive-age couples who fail to conceive naturally. Chromosomal aberrations have …

Detecting PCOS susceptibility loci from genome-wide association studies via iterative trend correlation based feature screening

X Dai, G Fu, R Reese - BMC bioinformatics, 2020 - Springer
Background Feature screening plays a critical role in handling ultrahigh dimensional data
analyses when the number of features exponentially exceeds the number of observations. It …

[PDF][PDF] Effect of Bushen Yangluan decoction combined with clomiphene citrate on ovulation and ovarian function in patients with infertility due to polycystic ovary …

D Zhang, L Jin, J Han, Y Song, H Song… - International Journal of …, 2021 - e-century.us
Objective: We aimed to investigate the effect of Bushen Yangluan (BSYL) decoction
combined with clomiphene citrate (CC) on ovulation and ovarian function in patients with …

Proteomic and clinical insights into polycystic ovary syndrome in adolescents

HM Gunn - 2022 - discovery.ucl.ac.uk
Despite its high prevalence, our understanding of the pathophysiology of polycystic ovary
syndrome (PCOS) is lacking. Consequently, the way we diagnose and manage this common …