Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Cryptococcosis is an infection of global significance, affecting both immunocompromised
and immunocompetent hosts. Traditionally, 2 main species of yeasts caused cryptococcosis …

Over the past ten years, standard diagnostics for cryptococcal meningitis in HIV-infected
persons have evolved from culture to India ink to detection of cryptococcal antigen (CrAg) …

Background Diagnosing invasive or chronic fungal infections is a challenge, particularly in
the immunocompromised host. Microscopy and culture remain the reference standard, but …

Cryptococcal meningitis is a leading cause of morbidity and mortality globally, especially in
people with advanced HIV disease. Cryptococcal meningitis is responsible for nearly 20% of …

Cryptococcal antigen (CrAg) detection could direct the timely initiation of antifungal therapy.
We searched MEDLINE and Embase for studies where CrAg detection in …

Invasive fungal infections continue to increase as at-risk populations expand. The high
associated morbidity and mortality with fungal diseases mandate the continued investigation …

Appropriate diagnosis of invasive fungal infections (IFIs) is critical due to the high rates of
morbidity and mortality, as well as the substantial economic burden, associated with the …

Cryptococcal meningitis persists as a significant source of morbidity and mortality in persons
with HIV/AIDS, particularly in sub-Saharan Africa. Despite increasing access to …

Abstract In 2017, 47,600 overdose deaths were reported to be associated with the abuse of
opioids, including prescription painkillers (eg oxycodone), opiates (eg heroin), or synthetic …