Primary aldosteronism (PA), the most common form of secondary hypertension, can be
either surgically cured or treated with targeted pharmacotherapy. PA is frequently …

Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …

We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …

Primary aldosteronism (PA) is the most common form of secondary hypertension. In many
cases, somatic mutations in ion channels and pumps within adrenal cells initiate the …

Primary aldosteronism is the most common single cause of hypertension and is potentially
curable when only one adrenal gland is the culprit. The importance of primary aldosteronism …

A substantial proportion of patients with hypertension have a low or suppressed renin. This
phenotype of low-renin hypertension (LRH) may be the manifestation of inherited genetic …

The primary physiological regulators of aldosterone production are Ang II, K+, and
adrenocorticotropic hormone. Other factors that have been proposed to modulate …

Abstract Purpose Adrenal incidentalomas (AIs) are incidentally discovered adrenal masses,
during an imaging study undertaken for other reasons than the suspicion of adrenal disease …

Primary aldosteronism is a secondary hypertensive disease caused by autonomous
aldosterone production that often caused by an aldosterone-producing adenoma (APA) …

Context The adrenal cortex consists of zona glomerulosa (ZG), fasciculata (ZF), and
reticularis. Aldosterone-producing cell clusters (APCCs) that strongly express aldosterone …