Objectives To review the literature and provide an update on the mechanisms of action and
therapeutic uses of oral colchicine in arthritis and inflammatory conditions. Methods We …

Purpose The aims of this article were to systematically review the literature about the
mechanism of action of colchicine in the multimodal pathology of acute inflammation …

We aimed to develop evidence-based multinational recommendations for the diagnosis and
management of gout. Using a formal voting process, a panel of 78 international …

Objective Hyperuricemia is a precursor to gout and is often present in other metabolic
diseases that are promoted by microbiome dysbiosis. We undertook this study to examine …

Objectives Despite the publication of hundreds of trials on gout and hyperuricemia,
management of these conditions remains suboptimal. We aimed to assess the quality and …

Objectives Weight loss is commonly recommended for gout, but the magnitude of the effect
has not been evaluated in a systematic review. The aim of this systematic review was to …

Objective. To produce consensus-based definitions of the US elementary lesions in gout
and to test their reliability in a web-based exercise. Methods. The process consisted of two …

Background Psoriasis is associated with metabolic, liver and cardiovascular comorbidity.
Secukinumab, a fully human monoclonal antibody that selectively neutralizes interleukin …

Background Allopurinol, a xanthine oxidase inhibitor, is considered one of the most effective
urate‐lowering drugs and is frequently used in the treatment of chronic gout. Objectives To …

Background Si-Miao-San (SMS) is a well-known traditional Chinese medicine. This study
aims to evaluate the anti-inflammatory effects of SMS on gouty arthritis and its potential …