[HTML][HTML] Mg bone implant: Features, developments and perspectives

Y Yang, C He, E Dianyu, W Yang, F Qi, D Xie, L Shen… - Materials & Design, 2020 - Elsevier
Mg and its alloys have been identified as promising bone implant materials owing to their
natural degradability, good biocompatibility and favorable mechanical properties …

Relapse of acute myeloid leukemia after allogeneic stem cell transplantation: immune escape mechanisms and current implications for therapy

T Sauerer, GF Velázquez, C Schmid - Molecular Cancer, 2023 - Springer
Acute myeloid leukemia (AML) is a heterogeneous disease characterized by the expansion
of immature myeloid cells in the bone marrow (BM) and peripheral blood (PB) resulting in …

Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation

C Toffalori, L Zito, V Gambacorta, M Riba, G Oliveira… - Nature medicine, 2019 - nature.com
Transplantation of hematopoietic cells from a healthy individual (allogeneic hematopoietic
cell transplantation (allo-HCT)) demonstrates that adoptive immunotherapy can cure blood …

Mechanisms of immune escape after allogeneic hematopoietic cell transplantation

R Zeiser, L Vago - Blood, The Journal of the American Society …, 2019 - ashpublications.org
Relapse of the original disease is a major cause of death after allogeneic hematopoietic cell
transplantation for acute leukemias. There is growing evidence that relapses may be …

How we perform haploidentical stem cell transplantation with posttransplant cyclophosphamide

SR McCurdy, L Luznik - Hematology 2014, the American …, 2019 - ashpublications.org
HLA-haploidentical hematopoietic stem cell transplantation is now one of the most
commonly employed alternative donor techniques, with most centers applying T-cell–replete …

Myeloablative and reduced-intensity conditioning in HLA-haploidentical peripheral blood stem cell transplantation using post-transplant cyclophosphamide

J Sugita, Y Kagaya, T Miyamoto, Y Shibasaki… - Bone Marrow …, 2019 - nature.com
We conducted two parallel prospective, multicenter, phase II studies to evaluate the safety
and efficacy of HLA-haploidentical peripheral blood stem cell transplantation using post …

Outcome of donor-derived TAA-T cell therapy in patients with high-risk or relapsed acute leukemia post allogeneic BMT

H Kinoshita, KR Cooke, M Grant, M Stanojevic… - Blood …, 2022 - ashpublications.org
Patients with hematologic malignancies relapsing after allogeneic blood or marrow
transplantation (BMT) have limited response to conventional salvage therapies, with an …

Treatment of AML relapse after allo-HCT

JA Webster, L Luznik, I Gojo - Frontiers in Oncology, 2021 - frontiersin.org
With advances in allogeneic hematopoietic stem cell transplant (allo-HCT), disease relapse
has replaced transplant-related mortality as the primary cause of treatment failure for …

Mechanisms of leukemia immune evasion and their role in relapse after haploidentical hematopoietic cell transplantation

PE Rovatti, V Gambacorta, F Lorentino… - Frontiers in …, 2020 - frontiersin.org
Over the last decade, the development of multiple strategies to allow the safe transfer from
the donor to the patient of high numbers of partially HLA-incompatible T cells has …

[HTML][HTML] Biology-driven approaches to prevent and treat relapse of myeloid neoplasia after allogeneic hematopoietic stem cell transplantation

R Zeiser, DW Beelen, W Bethge, M Bornhäuser… - Biology of Blood and …, 2019 - Elsevier
The curative potential of allogeneic hematopoietic cell transplantation (allo-HCT) in the
treatment of acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS) …