Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …

Mycobacterium africanum consists of two phylogenetically distinct lineages within the
Mycobacterium tuberculosis complex, known as M. africanum West African 1 and M …

Factors driving the increase in drug-resistant tuberculosis (TB) in the Eastern Cape
Province, South Africa, are not understood. A convenience sample of 309 drug-susceptible …

Rifampin resistance in clinical isolates of Mycobacterium tuberculosis arises primarily
through the selection of bacterial variants harboring mutations in the 81-bp rifampin …

Members of the Mycobacterium tuberculosis complex (MTBC) cause a serious disease with
similar pathology, tuberculosis; in this review, bovine tuberculosis will be considered as …

Widespread resistance to first-line TB drugs is a major problem that will likely only be
resolved through the development of new drugs with novel mechanisms of action. We have …

Rapid and accurate strain identification is paramount in the battle against microbial
outbreaks, and several subtyping approaches have been developed. One such method …

Background. Although several hot spots of multidrug-resistant tuberculosis have been
identified on the African continent, extensive drug resistance (XDR) has not been reported …

Objectives To compare mutations in the quinolone resistance-determining region of the gyrA
gene and flanking sequences with the MICs of ofloxacin and moxifloxacin for Mycobacterium …

The epidemiology of tuberculosis (TB) in the United States is changing as the incidence of
disease becomes more concentrated in foreign-born persons. Mycobacterium bovis appears …