Diabetes is a multi-faceted disorder with increasing prevalence and rising healthcare costs.
The burden of diabetes is increased because of associated complications affecting nearly all …

The function and morphology of β-cells is largely dependent on insulin demand. As β-cells
cover a bigger cell proportion in pancreas islets, changes of insulin producer cells affect the …

Glucose homeostasis is maintained and tightly regulated via production of key hormones
that control the uptake and metabolism of glucose. β-cells, which secrete insulin, are the …

Pancreatic beta cells within the islets of Langerhans contribute to the regulation of glucose
homeostasis by secretion of insulin, a hormone that stimulates the uptake of glucose by liver …

In conclusion,[18F] exendin-4 is a promising radiotracer for beta cell imaging due to its
specific labeling of the islets and concomitant low kidney retention. These properties make it …

The International Diabetes Federation has recently announced that 415 million people
worldwide currently have diabetes, and this incidence is predicted to increase to 642 million …