Iron is an essential element for key cellular metabolic processes. However, transfusional
iron overload (IOL) may result in significant cellular toxicity. IOL occurs in transfusion …

In 2008 the first evidence-based Canadian consensus guideline addressing the diagnosis,
monitoring and management of transfusional iron overload in patients with myelodysplastic …

Pretransplant values of serum ferritin, albumin, and peripheral blood counts were previously
suggested to provide prognostic information about hematopoietic cell transplantation (HCT) …

Iron overload (IO) reflected by elevated ferritin is associated with increased mortality in
myelodysplastic syndromes (MDS), however, ferritin is an imperfect metric. Elevated labile …

Despite the benefits of red blood cell (RBC) transfusion therapy, it can render patients
vulnerable to iron overload. The excess iron deposits in various body tissues cause severe …

Background: Pre-transplantation serum ferritin (SF) has been considered to be a potential
prognostic biomarker in patients undergoing allogeneic hematopoietic stem cell …

Early diagnostics of ovarian cancer is difficult, because there are no symptoms until the
disease has progressed to an advanced stage. As urine contains many intrinsic …

Clinical presentation and laboratory data are often too unspecific to distinguish the onset or
activity of graft-versus-host disease (GvHD) from infections or toxicity. Antigen-presenting …

This is the first prospective study of deferasirox in adult allogeneic hematopoietic stem cell
transplant recipients with transfusional iron overload in hematologic malignancies. Patients …

Data on post-transplant iron overload (IO) are scarce in pediatrics. We conducted a
prospective multicenter cohort study (Leucémie de l'Enfant et de l'Adolescent cohort) to …