A distinctive subset of metastatic breast cancer (MBC) is oligometastatic disease, which is
characterized by single or few detectable metastatic lesions. The existing treatment …

Background Metastatic breast cancer is not a curable disease, but women with metastatic
disease are living longer. Surgery to remove the primary tumour is associated with an …

Background The MF07-01 trial is a multicenter, phase III, randomized, controlled study
comparing locoregional treatment (LRT) followed by systemic therapy (ST) with ST alone for …

Background The role of locoregional treatment in women with metastatic breast cancer at
first presentation is unclear. Preclinical evidence suggests that such treatment might help the …

Background The aim of this randomized clinical trial was to evaluate the overall survival
(OS) data of patients diagnosed with de novo stage IV breast cancer (BC) who received …

Background Breast cancer brain metastases (BCBM) are the most fatal, with limited survival
in all breast cancer distant metastases. These patients are deemed to be incurable. Thus …

Introduction The role of primary tumor excision in patients with stage IV breast cancer is
unclear. Therefore, a meta-analysis of relevant studies was performed to determine whether …

BACKGROUND: Multiple studies have suggested that resection of the primary tumor
improves survival in patients with stage IV breast cancer, yet in the era of targeted therapy …

OBJECTIVE: Recent studies indicate that removal of the primary tumour may have a
beneficial effect on mortality risk of patients with primary distant metastatic breast cancer …

Purpose Retrospective analyses suggest patients with stage IV breast cancer who undergo
breast surgery have improved survival. We sought to determine whether surgery and other …