Large-Scale prediction of human protein− protein interactions from amino acid sequence based on latent topic features

XY Pan, YN Zhang, HB Shen - Journal of proteome research, 2010 - ACS Publications
Protein− protein interaction (PPI) is at the core of the entire interactomic system of any living
organism. Although there are many human protein− protein interaction links being …

Mining from protein–protein interactions

H Mamitsuka - Wiley Interdisciplinary Reviews: Data Mining and …, 2012 - Wiley Online Library
Proteins are important cellular molecules, and interacting protein pairs provide biologically
important information, such as functional relationships. We focus on the problem of …

Critical assessment of sequence-based protein-protein interaction prediction methods that do not require homologous protein sequences

Y Park - BMC bioinformatics, 2009 - Springer
Background Protein-protein interactions underlie many important biological processes.
Computational prediction methods can nicely complement experimental approaches for …

Protein interaction networks: protein domain interaction and protein function prediction

Y Qi, WS Noble - Handbook of Statistical Bioinformatics, 2011 - Springer
Most of a cell's functional processes involve interactions among proteins, and a key
challenge in proteomics is to better understand these complex interaction graphs at a …

Reconstruction of metabolic pathways by combining probabilistic graphical model-based and knowledge-based methods

Q Qi, J Li, J Cheng - BMC proceedings, 2014 - Springer
Automatic reconstruction of metabolic pathways for an organism from genomics and
transcriptomics data has been a challenging and important problem in bioinformatics …

Inferring the Brassica rapa Interactome Using Protein–Protein Interaction Data from Arabidopsis thaliana

J Yang, K Osman, M Iqbal, DJ Stekel, Z Luo… - Frontiers in Plant …, 2013 - frontiersin.org
Following successful completion of the Brassica rapa sequencing project, the next step is to
investigate functions of individual genes/proteins. For Arabidopsis thaliana, large amounts of …

The Transcriptome Analysis of Circular RNAs Between the Doxorubicin-Induced Cardiomyocytes and Bone Marrow Mesenchymal Stem Cells-Derived Exosomes …

Y Wei, H Wei, C Tian, Q Wu, D Li… - … Chemistry & High …, 2024 - ingentaconnect.com
Aim: To analyze the sequencing results of circular RNAs (circRNAs) in cardiomyocytes
between the doxorubicin (DOX)-injured group and exosomes treatment group. Moreover, to …

Yeast protein–protein interaction binding sites: prediction from the motif–motif, motif–domain and domain–domain levels

E Pang, K Lin - Molecular BioSystems, 2010 - pubs.rsc.org
Interacting proteins can contact with each other at three different levels: by a domain binding
to another domain, by a domain binding to a short protein motif, or by a motif binding to …

Triangle network motifs predict complexes by complementing high-error interactomes with structural information

B Andreopoulos, C Winter, D Labudde, M Schroeder - BMC bioinformatics, 2009 - Springer
Background A lot of high-throughput studies produce protein-protein interaction networks
(PPINs) with many errors and missing information. Even for genome-wide approaches, there …

Multi-level learning: improving the prediction of protein, domain and residue interactions by allowing information flow between levels

KY Yip, PM Kim, D McDermott, M Gerstein - BMC bioinformatics, 2009 - Springer
Background Proteins interact through specific binding interfaces that contain many residues
in domains. Protein interactions thus occur on three different levels of a concept hierarchy …