The majority of the well-known pharmacogenomics research used in the medical sciences
contributes to our understanding of medication interactions. It has a significant impact on …

Chemical exposomes can now be comprehensively measured in human blood, but
knowledge of their variability and longitudinal stability is required for robust application in …

Noise-induced hearing loss (NIHL) is a major cause of hearing impairment, yet no FDA-
approved drugs exist to prevent it. Targeting the mitogen activated protein kinase (MAPK) …

Cannabidiol (CBD) is a non-psychoactive compound derived from Cannabis sativa. It has
demonstrated promising effects in combating inflammation and holds potential as a …

Precision dosing strategies require accounting for between‐patient variability in
pharmacokinetics (PK), affecting drug exposure, and in pharmacodynamics (PD), affecting …

Pharmacokinetics plays a central role in understanding the significant interindividual
differences that exist in drug metabolism and response. Effectively addressing these …

Over the past 20 years, quantitative proteomics has contributed a wealth of protein
expression data, which are currently used for a variety of systems pharmacology …

“Special Section on New and Emerging Areas and Technologies in Drug Metabolism and
Disposition, Part I” presents nine articles mainly contributed by the current Editorial Advisory …

Noise-induced hearing loss (NIHL) is a major cause of hearing impairment and is linked to
dementia and mental health conditions, yet no FDA-approved drugs exist to prevent it …

Abstract Background and Objectives Clearances and the area under the plasma
concentration–time curve extrapolated to infinity (AUC0–∞) of intravenous (IV) and oral …