Potential roles of PIWI-interacting RNAs in lung cancer

Z Jian, Y Han, H Li - Frontiers in Oncology, 2022 - frontiersin.org
Lung cancer is a malignant tumor with high morbidity and mortality in the world today.
Emerging evidence suggests that PIWI-interacting RNAs (piRNAs) are aberrantly expressed …

Ku80 gene knockdown by the CRISPR/Cas9 technique affects the biological functions of human thyroid carcinoma cells

Y Fan, J Li, W Wei, H Fang, Y Duan, N Li… - Oncology …, 2019 - spandidos-publications.com
In the present study, to evaluate the role of Ku80 in thyroid carcinoma (TC), 86 thyroid tissue
samples from patients with a spectrum of thyroid disorders were examined for protein levels …

PIWIL2 restrains the progression of thyroid cancer via interaction with miR-146a-3p

X Lu, Q Zhu, H Du, M Gu, X Li - BMC Endocrine Disorders, 2023 - Springer
Objective The classical role of PIWIL2 is to regulate reproduction by binding to piRNA, but its
tumor-related function has received increasing attention in recent years. This study aims to …

Novel piRNA MW557525 regulates the growth of Piwil2-iCSCs and maintains their stem cell pluripotency

L Jin, Z Zhang, Z Wang, X Tan, Z Wang, L Shen… - Molecular Biology …, 2022 - Springer
Background CSCs play an important role in tumor development. Some studies have
demonstrated that piRNAs participate in the progression of various cancers. However, the …

[HTML][HTML] 肿瘤样干细胞来源的外泌体促进人脐带间充质干细胞的增殖和

张丹, 何大维, 李典, 唐波, 胡东, 郭文浩… - Journal of Southern …, 2018 - ncbi.nlm.nih.gov
肿瘤样干细胞来源的外泌体促进人脐带间充质干细胞的增殖和- PMC Back to Top Skip to main
content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

PIWIL2 stabilizes β-catenin to promote cell cycle and proliferation in tumor cells

B Qiu, J Zeng, X Zhao, L Huang, T Ma, Y Zhu… - Biochemical and …, 2019 - Elsevier
PIWIL2 belongs to the PIWI protein subfamily and is widely expressed in a variety of tumors.
Previous studies have shown that PIWIL2 has the characteristics of oncogene. Recently we …

Update on: proteome analysis in thyroid pathology–part II: overview of technical and clinical enhancement of proteomic investigation of the thyroid lesions

I Piga, S Casano, A Smith, S Tettamanti… - Expert Review of …, 2018 - Taylor & Francis
Introduction: An accurate diagnostic classification of thyroid lesions remains an important
clinical aspect that needs to be addressed in order to avoid 'diagnostic'thyroidectomies …

Cancer stem-like cell-derived exosomes promotes the proliferation and invasion of human umbilical cord blood-derived mesenchymal stem cells

D Zhang, D He, D Li, B Tang, D Hu, W Guo… - … Fang yi ke da xue xue …, 2018 - europepmc.org
Objective To investigate the effect of Piwil2-induced cancer stem-like cell (Piwil2-iCSC)-
derived exosomes on the proliferation, migration and invasion of human umbilical cord …

PiRNA MW557525 Promotes the Vitality and Pluripotency of Piwil2-iCSCs by Regulating NOP56.

L Jin, Z Zhang, Z Wang, X Tan, Z Wang, L Shen… - 2022 - researchsquare.com
Background: CSCs play an important role in tumor development. Some studies have
demonstrated that piRNAs participate in the progression of various cancers. However, the …