Covering: up to June 2020 Ribosomally-synthesized and post-translationally modified
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …

Defensins are a family of cationic antimicrobial peptides active against a broad range of
infectious microbes including bacteria, viruses and fungi, playing important roles as innate …

Site-specific protein modification is a widely-used biochemical tool. However, there are
many challenges associated with the development of protein modification techniques, in …

This Review explores the class of plant-derived macrocyclic peptides called cyclotides. We
include an account of their discovery, characterization, and distribution in the plant kingdom …

Bacteriocins are low molecular weight peptides secreted by the predator bacterial cells to kill
sensitive cells present in the same ecosystem competing for food and other nutrients …

As a versatile therapeutic modality, peptides attract much attention because of their great
binding affinity, low toxicity, and the capability of targeting traditionally “undruggable” protein …

Breaking and forming peptidyl bonds are fundamental biochemical reactions in protein
chemistry. Unlike proteases that are abundantly available, fast-acting ligases are rare …

Bacteriocins are a huge family of ribosomally synthesized peptides known to exhibit a range
of bioactivities, most predominantly antibacterial activities. Bacteriocins from lactic acid …

Cyclic peptides are molecules that are already used as drugs in therapies approved for
various pharmacological activities, for example, as antibiotics, antifungals, anticancer, and …

Conspectus The coupling of an α-ketoacid and a hydroxylamine (KAHA ligation) affords
amide bonds under aqueous, acidic conditions without the need for protecting groups or …