In-patient evolution of a high-persister Escherichia coli strain with reduced in vivo antibiotic susceptibility

JB Parsons, AE Sidders, AZ Velez… - Proceedings of the …, 2024 - National Acad Sciences
Gram-negative bacterial bloodstream infections (GNB-BSI) are common and frequently
lethal. Despite appropriate antibiotic treatment, relapse of GNB-BSI with the same bacterial …

[HTML][HTML] Exploring the Potential Influence of the Human Gut Microbiota on the Gut Resistome: A Systematic Review

J Fri, M Raphalalani, LG Mavhandu-Ramarumo… - Microbiology …, 2024 - mdpi.com
Antibiotic resistance is a global health problem. The human gut microbiome is implicated in
the dynamics of antibiotic resistance acquisition and transmission, with the gut microbiota …

The role of metagenomic next-generation sequencing in diagnosing and managing post-kidney transplantation infections

H Wu, H Cao, X Gao, C Shi, L Wang… - Frontiers in Cellular and …, 2025 - frontiersin.org
Kidney transplantation (KT) is a life-saving treatment for patients with end-stage renal
disease, but post-transplant infections remain one of the most significant challenges. These …

The Effects of L-Lysine-α-oxidase Enzyme and Trichoderma harzianum Rifai Culture Liquid on the Formation of Biofilms by Uropathogenic Multiresistant E. coli

A Senyagin, N Sachivkina, M Das, V Semenova… - Fermentation, 2023 - mdpi.com
In this study, the data of the antagonistic action of the enzyme L-lysine-α-oxidase in relation
to clinical isolates of multiresistant uropathogenic Escherichia coli isolated from patients …

Comparative study of virulence potential, phylogenetic origin, CRISPR-Cas regions and drug resistance of Escherichia coli isolates from urine and other clinical …

A Dziuba, S Dzierżak, A Sodo… - Frontiers in …, 2023 - frontiersin.org
Introduction Urinary tract infections (UTI), among which the main etiological factor is
uropathogenic Escherichia coli (UPEC, E. coli), remain an important issue for clinicians. The …

Clinical and molecular analyses of recurrent gram-negative bloodstream infections

A Bock, BM Hanson, F Ruffin, JB Parsons… - Clinical Infectious …, 2023 - academic.oup.com
Background The causes and clinical characteristics of recurrent gram-negative bacterial
bloodstream infections (GNB-BSI) are poorly understood. Methods We used a cohort of …

Antimicrobial and anti-biofilm properties of oleuropein against Escherichia coli and fluconazole-resistant isolates of Candida albicans and Candida glabrata

MA Esfandiary, AR Khosravi, S Asadi, D Nikaein… - BMC microbiology, 2024 - Springer
Side effects associated with antimicrobial drugs, as well as their high cost, have prompted a
search for low-cost herbal medicinal substances with fewer side effects. These substances …

KRAS mutations promote the intratumoral colonization of enterotoxigenic bacteroides fragilis in colorectal cancer through the regulation of the miRNA3655/SURF6 …

Y Chen, S Liu, S Tan, Y Zheng, Y Chen, C Yang… - Gut …, 2024 - Taylor & Francis
ABSTRACT KRAS mutations are associated with poor prognosis in colorectal cancer (CRC).
Although the association between the gut microbiota and CRC has been extensively …

Outer membrane vesicles from Escherichia coli are efficiently internalized by macrophage cells and alter their inflammatory response

C Guangzhang, F Fangfang, D Siqian, X Xinyi… - Microbial …, 2023 - Elsevier
The release of extracellular vesicles (EV) by pathogenic microbes is considered an
alternative cell-to-cell transport of macromolecules transport mechanism. In Gram-negative …

The Characteristics of Extended-Spectrum β-Lactamases (ESBLs)-Producing Escherichia coli in Bloodstream Infection

R Li, H Xu, H Tang, J Shen, Y Xu - Infection and Drug Resistance, 2023 - Taylor & Francis
Background Bloodstream infection (BSI) is a common type of infection frequently diagnosed
in clinics. The emergence and spread of ESBLs-producing Escherichia coli (E. coli) has …