Although gray matter (GM) damages caused by long term and excessive alcohol
consumption have long been reported, the structural neuroimaging findings on alcohol-use …

Bipolar disorder (BD) and alcohol use disorders (AUDs) are usually comorbid, and both
have been associated with significant neurocognitive impairment. Patients with the BD-AUD …

Background: The literature on grey-matter volume alterations in bipolar disorder is
heterogeneous in its findings. Methods: Using effect-size differential mapping, we conducted …

Objectives Bipolar disorder (BD) is a psychiatric disorder with high morbidity and mortality
that cannot be distinguished from major depressive disorder (MDD) until the first manic …

Objectives Bipolar I disorder (BD‐I) is associated with gray matter volume (GMV) alterations
in neural regions important for emotional regulation. Reductions found in patients with …

Objective: Cortical and subcortical gray matter abnormalities have been reported in
individuals at high genetic risk for bipolar disorder, but the findings are inconsistent. The aim …

OBJECTIVES: To determine whether long-term data implicate a negative effect of alcohol-
use disorders (AUDs) on time to remission, risk of mood episode recurrence, and risk of …

Substance use disorders and mood disorders are highly comorbid and confer a high risk for
adverse outcomes. However, data are limited on the neurodevelopmental basis of this …

Background Symptomatic phases in bipolar disorder (BD) are hypothesized to result from a
hypersensitive behavioral activation system (BAS) being sensitive to potential rewards …

Objective Explore interrelationships between suicide attempt history (Objective 1) or suicide
attempt severity (Objective 2) with prefrontal cortex gray matter (PFCGM) volume and illness …