Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …

Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

Doxorubicin (DOX) is a chemotherapeutic agent frequently used for the treatment of a variety
of tumor types, such as breast cancer. Despite the long history of DOX, the mechanistic …

Doxorubicin (DOX), also known as adriamycin, is a DNA topoisomerase II inhibitor and
belongs to the family of anthracycline anticancer drugs. DOX is used for the treatment of a …

Over last decades, most antitumor therapeutic strategies have focused on apoptosis,
however, apoptosis resistance and immunological silence usually led to treatment failure. In …

Despite advances in diagnostic tools and therapeutic options, treatment resistance remains
a challenge for many cancer patients. Recent studies have found evidence that autophagy …

Cancer formation is a highly regulated and complex process, largely dependent on its
microenvironment. This complexity highlights the need for developing novel target-based …

The complicated stepwise lysosomal degradation process known as autophagy is in charge
of destroying and eliminating damaged organelles and defective cytoplasmic components …

Tumor cells can undergo diverse responses to cancer therapy. While apoptosis represents
the most desirable outcome, tumor cells can alternatively undergo autophagy and …

Berberine (BBR) is a natural isoquinoline alkaloid, which is used in traditional medicine for
its anti‐microbial, anti‐protozoal, anti‐diarrhoeal activities. Berberine interacts with DNA and …