The gut microbiota and colorectal surgery outcomes: facts or hype? A narrative review

A Agnes, C Puccioni, D D'Ugo, A Gasbarrini, A Biondi… - BMC surgery, 2021 - Springer
Background The gut microbiota (GM) has been proposed as one of the main determinants of
colorectal surgery complications and theorized as the “missing factor” that could explain still …

Systematic review of preoperative and intraoperative colorectal Anastomotic Leak Prediction Scores (ALPS)

ML Venn, RL Hooper, T Pampiglione, DG Morton… - BMJ open, 2023 - bmjopen.bmj.com
Objective To systematically review preoperative and intraoperative Anastomotic Leak
Prediction Scores (ALPS) and validation studies to evaluate performance and utility in …

Systemic versus Oral and Systemic Antibiotic Prophylaxis (SOAP) study in colorectal surgery: prospective randomized multicentre trial

G Papp, G Saftics, BE Szabó, J Baracs… - British Journal of …, 2021 - academic.oup.com
Background There is no consensus regarding the role of mechanical bowel preparation
(MBP) and oral antibiotic prophylaxis (OABP) in reducing postoperative complications in …

Influence of the microbiome on anastomotic leak

AJ Williamson, JC Alverdy - Clinics in Colon and Rectal …, 2021 - thieme-connect.com
Despite advances in surgical technique and the expanded use of antibiotics, anastomotic
leak remains a dreaded complication leading to increased hospital length of stay, morbidity …

[PDF][PDF] Mechanical bowel preparation and antibiotics in elective colorectal surgery: network meta-analysis

J Tan, ÉJ Ryan, MG Davey, FT McHugh, B Creavin… - BJS open, 2023 - academic.oup.com
Background The use of intravenous antibiotics at anaesthetic induction in colorectal surgery
is the standard of care. However, the role of mechanical bowel preparation, enemas, and …

The role of preoperative mechanical bowel preparation and oral antibiotics in prevention of anastomotic leakage following restorative resection for primary rectal …

RB Hansen, R Balachandran, TN Valsamidis… - International Journal of …, 2023 - Springer
Purpose Anastomotic leakage after colorectal cancer resection is a feared postoperative
complication seen among up till 10–20% of patients, with a higher risk following rectal …

Influencing factors in surgical decision‐making: a qualitative analysis of colorectal surgeons' experiences of postoperative complications

CN Bisset, SJ Moug, R Oliphant, N Dames… - Colorectal …, 2024 - Wiley Online Library
Aim When making anastomotic decisions in rectal cancer surgery, surgeons must consider
the risk of anastomotic leakage, which bears implications for the patient's quality of life …

Robotic-assisted repair of complex ventral hernia: can it pay off?

B Dauser, N Hartig, M Vedadinejad, E Kirchner… - Journal of Robotic …, 2021 - Springer
Pressure on health care providers is growing due to capping of remuneration for medical
services in most Western European countries. We wanted to investigate, if robotic-assisted …

Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short-term outcomes following left-sided …

AM Golder, CW Steele, D Conn, GJ MacKay… - BJS open, 2019 - academic.oup.com
Background Preoperative oral antibiotics in addition to intravenous antibiotics and
mechanical bowel preparation (MBP) may influence the gut microbiome and reduce both the …

Mechanical and oral antibiotic bowel preparation versus no bowel preparation in right and left colectomy: subgroup analysis of MOBILE trial

L Koskenvuo, T Lehtonen, S Koskensalo… - BJS open, 2021 - academic.oup.com
Background In retrospective series, mechanical and oral antibiotic bowel preparation
(MOABP) has been reported to reduce surgical-site infections (SSIs) after colectomy …