Polyphenols in metabolic diseases

A Gasmi, PK Mujawdiya, S Noor, R Lysiuk… - Molecules, 2022 - mdpi.com
Polyphenols (PPs) are a large group of phytochemicals containing phenolic rings with two or
more hydroxyl groups. They possess powerful antioxidant properties, multiple therapeutic …

Health Benefits of Silybum marianum: Phytochemistry, Pharmacology, and Applications

X Wang, Z Zhang, SC Wu - Journal of agricultural and food …, 2020 - ACS Publications
Silybum marianum (SM), a well-known plant used as both a medicine and a food, has been
widely used to treat various diseases, especially hepatic diseases. The seeds and fruits of …

The potential and action mechanism of polyphenols in the treatment of liver diseases

S Li, HY Tan, N Wang, F Cheung… - … medicine and cellular …, 2018 - Wiley Online Library
Liver disease, involving a wide range of liver pathologies from fatty liver, hepatitis, and
fibrosis to cirrhosis and hepatocellular carcinoma, is a serious health problem worldwide. In …

[HTML][HTML] Bisphenol A induces apoptosis, oxidative stress and inflammatory response in colon and liver of mice in a mitochondria-dependent manner

K Wang, Z Zhao, W Ji - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Bisphenol A (BPA), a widely used industrial compound worldwide, was recently classified as
an environmental toxicant. The intestines and liver are responsible for detoxification in …

[HTML][HTML] The influence of polyphenols on metabolic disorders caused by compounds released from plastics-Review

W Żwierełło, A Maruszewska, M Skórka-Majewicz… - Chemosphere, 2020 - Elsevier
Persistent organic pollutants (POPs) released from plastics into water, soil and air are
significant environmental and health problem. Continuous exposure of humans to these …

Adverse Effects of Bisphenol A on the Liver and Its Underlying Mechanisms: Evidence from In Vivo and In Vitro Studies

ASAR Abdulhameed, V Lim, H Bahari… - BioMed Research …, 2022 - Wiley Online Library
BPA is a known endocrine‐disrupting agent that is capable of binding to the estrogen
receptor and has exhibited adverse effects in many laboratory animal and in vitro studies …

Nanotherapeutic silibinin: an insight of phytomedicine in healthcare reformation

A Takke, P Shende - Nanomedicine: Nanotechnology, Biology and …, 2019 - Elsevier
Most of the herbal origin drugs possess water insoluble active constituents which lower the
bioavailability and increase systemic clearance after administration of repeated or higher …

Modulatory effects of bisphenol A on the hepatic immune response

YA Gebru, MG Pang - Environmental Pollution, 2023 - Elsevier
The liver is a primary line of defense for protection from external substances next to the
intestinal barrier. As a result, the hepatic immune system plays a central role in liver …

Silymarin and Inflammation: Food for Thoughts

PF Surai, A Surai, K Earle-Payne - Antioxidants, 2024 - mdpi.com
Inflammation is a vital defense mechanism, creating hostile conditions for pathogens,
preventing the spread of tissue infection and repairing damaged tissues in humans and …

Bisphenol S-induced chronic inflammatory stress in liver via peroxisome proliferator-activated receptor γ using fish in vivo and in vitro models

W Qiu, M Yang, J Liu, H Xu, S Luo, M Wong… - Environmental …, 2019 - Elsevier
Bisphenol S (BPS) has been widely used as a bisphenol alternative in recent few years.
However, with mounting evidence suggesting that the presence of BPS in the environment …