Septins: the fourth component of the cytoskeleton

S Mostowy, P Cossart - Nature reviews Molecular cell biology, 2012 - nature.com
Septins belong to a family of proteins that is highly conserved in eukaryotes and is
increasingly recognized as a novel component of the cytoskeleton. All septins are GTP …

Endocytosis of viruses and bacteria

P Cossart, A Helenius - Cold Spring Harbor perspectives …, 2014 - cshperspectives.cshlp.org
Of the many pathogens that infect humans and animals, a large number use cells of the host
organism as protected sites for replication. To reach the relevant intracellular compartments …

Modulation of the sigma-1 receptor–IRE1 pathway is beneficial in preclinical models of inflammation and sepsis

DA Rosen, SM Seki, A Fernández-Castañeda… - Science translational …, 2019 - science.org
Sepsis is an often deadly complication of infection in which systemic inflammation damages
the vasculature, leading to tissue hypoperfusion and multiple organ failure. Currently, the …

Vimentin as a multifaceted player and potential therapeutic target in viral infections

I Ramos, K Stamatakis, CL Oeste… - International journal of …, 2020 - mdpi.com
Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal
functions, and therefore in basic cellular processes such as cell division and migration …

Chlamydial intracellular survival strategies

RJ Bastidas, CA Elwell… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen and the
causative agent of blinding trachoma. Although Chlamydia is protected from humoral …

[PDF][PDF] Chlamydia psittaci: update on an underestimated zoonotic agent

MR Knittler, K Sachse - Pathogens and disease, 2015 - researchgate.net
Chlamydia (C.) psittaci is an economically relevant pathogen in poultry and pet birds, where
it causes psittacosis/ornithosis, and also a human pathogen causing atypical pneumonia …

Intracellular lifestyle of Chlamydia trachomatis and host–pathogen interactions

K Stelzner, N Vollmuth, T Rudel - Nature Reviews Microbiology, 2023 - nature.com
In recent years, substantial progress has been made in the understanding of the intracellular
lifestyle of Chlamydia trachomatis and how the bacteria establish themselves in the human …

The Lipid Transfer Protein CERT Interacts with the Chlamydia Inclusion Protein IncD and Participates to ER-Chlamydia Inclusion Membrane Contact Sites

I Derré, R Swiss, H Agaisse - PLoS pathogens, 2011 - journals.plos.org
Bacterial pathogens that reside in membrane bound compartment manipulate the host cell
machinery to establish and maintain their intracellular niche. The hijacking of inter-organelle …

The cytoskeleton in cell-autonomous immunity: structural determinants of host defence

S Mostowy, AR Shenoy - Nature Reviews Immunology, 2015 - nature.com
Host cells use antimicrobial proteins, pathogen-restrictive compartmentalization and cell
death in their defence against intracellular pathogens. Recent work has revealed that four …

Strategies used by bacteria to grow in macrophages

G Mitchell, C Chen, DA Portnoy - Myeloid Cells in Health and …, 2017 - Wiley Online Library
Intracellular bacterial pathogens cause a wide range of diseases and significantly contribute
to the morbidity and mortality associated with infectious diseases worldwide (1‐16)(Table 1) …