Fibrin: a versatile scaffold for tissue engineering applications

TAE Ahmed, EV Dare, M Hincke - Tissue Engineering Part B …, 2008 - liebertpub.com
Tissue engineering combines cell and molecular biology with materials and mechanical
engineering to replace damaged or diseased organs and tissues. Fibrin is a critical blood …

Pharmacological agents and impairment of fracture healing: what is the evidence?

I Pountos, T Georgouli, TJ Blokhuis, HC Pape… - Injury, 2008 - Elsevier
Bone healing is an extremely complex process which depends on the coordinated action of
several cell lineages on a cascade of biological events, and has always been a major …

Proliferation and differentiation potential of human adipose‐derived mesenchymal stem cells isolated from elderly patients with osteoporotic fractures

HT Chen, MJ Lee, CH Chen… - Journal of cellular …, 2012 - Wiley Online Library
Aging has less effect on adipose‐derived mesenchymal stem cells (ADSCs) than on bone
marrow‐derived mesenchymal stem cells (BMSCs), but whether the fact holds true in stem …

[HTML][HTML] Homing and restorative effects of bone marrow-derived mesenchymal stem cells on cisplatin injured ovaries in rats

J Liu, H Zhang, Y Zhang, N Li, Y Wen, F Cao, H Ai… - Molecules and cells, 2014 - Elsevier
Premature ovarian failure (POF) is a long-term adverse effect of chemotherapy treatment.
However, current available treatment regimens are not optimal. Emerging evidence …

Localized nanoparticle‐mediated delivery of miR‐29b normalizes the dysregulation of bone homeostasis caused by osteosarcoma whilst simultaneously inhibiting …

FE Freeman, P Dosta, LC Shanley… - Advanced …, 2023 - Wiley Online Library
Patients diagnosed with osteosarcoma undergo extensive surgical intervention and
chemotherapy resulting in dismal prognosis and compromised quality of life owing to poor …

The therapeutic potential of mesenchymal stem cells: Cell-& tissue-based therapy

SC Picinich, PJ Mishra, PJ Mishra, J Glod… - Expert opinion on …, 2007 - Taylor & Francis
Mesenchymal stem cells (MSCs) are multipotent cells with a number of potential therapeutic
applications. At present, they are being used in a clinical trial for the treatment of myocardial …

Survival of Transplanted Rat Bone Marrow-Derived Osteogenic Stem Cells In Vivo

CE Zimmermann, M Gierloff, J Hedderich… - … Engineering Part A, 2011 - liebertpub.com
This study was designed to trace bone marrow-derived stromal cells (MSC) after
implantation in an ectopic rat model of bone tissue engineering. MSC were isolated from …

[HTML][HTML] The influence of gap size on the development of fracture union with a micro external fixator

R Meeson, M Moazen, A Sanghani-Kerai… - Journal of the …, 2019 - Elsevier
Increasingly, the rat femoral fracture model is being used for preclinical investigations of
fracture healing, however, the effect of gap size and its influence on mechanobiology is not …

A spheroid model of early and late‐stage osteosarcoma mimicking the divergent relationship between tumor elimination and bone regeneration

FE Freeman, R Burdis, OR Mahon… - Advanced Healthcare …, 2022 - Wiley Online Library
Osteosarcoma is the most diagnosed bone tumor in children. The use of tissue engineering
strategies after malignant tumor resection remains a subject of scientific controversy. As a …

[HTML][HTML] Mesenchymal stromal cells for bone sarcoma treatment: Roadmap to clinical practice

A Stamatopoulos, T Stamatopoulos, Z Gamie… - Journal of bone …, 2019 - Elsevier
Over the past few decades, there has been growing interest in understanding the molecular
mechanisms of cancer pathogenesis and progression, as it is still associated with high …