Prions are infectious proteins and over the past few decades, some prions have become
renowned for their causative role in several neurodegenerative diseases in animals and …

Simple Summary Aside from its well-established role in prion disorders, in the last decades
the significance of cellular prion protein (PrPC) expression in human cancers has attracted …

Cancer stem cells are implicated in tumor progression, metastasis, and recurrence, although
the exact mechanisms remain poorly understood. Here, we show that the expression of …

Background and objective Early detection of colon adenomas at high risk of progression and
early-stage colorectal cancer (CRC) is an effective approach to reduce CRC death rates …

Abstract Introduction High prion protein (PrP) levels are associated with breast, colon and
gastric cancer resistance to treatment and with a poor prognosis for the patients. However …

Prion protein (PrPc) has been previously reported to be involved in gastric cancer (GC)
development and progression. However, the association between expression of PrPc and …

Glioblastomas (GBMs) are resistant to current therapy protocols and identification of
molecules that target these tumors is crucial. Interaction of secreted heat-shock protein 70 …

Despite its multi-faceted role in neurodegenerative diseases, the physiological function of
the prion protein (PrP) has remained elusive. On the basis of its evolutionary relationship to …

PrPc is expressed in various tumors and is associated with cancer progression, but previous
studies have shown conflicting results regarding its relationship with patient prognosis …

Inherited mutations are known to cause familial cancers. However, the cause of sporadic
cancers, which likely represent the majority of cancers, is yet to be elucidated. Sporadic …