Taking a step back from testing: Preanalytical considerations in molecular infectious disease diagnostics

S Conrad, AG Kanegusuku, SE Conklin - Clinical Biochemistry, 2023 - Elsevier
Recent studies evaluating the preanalytical factors that impact the outcome of nucleic-acid
based methods for the confirmation of SARS-CoV-2 have illuminated the importance of …

Accelerating the development and validation of liquid biopsy for early cancer screening and treatment tailoring

D Horgan, T Čufer, F Gatto, I Lugowska, D Verbanac… - Healthcare, 2022 - mdpi.com
Liquid biopsy (LB) is a minimally invasive method which aims to detect circulating tumor-
derived components in body fluids. It provides an alternative to current cancer screening …

Implementing individualized quality control plans and managing risk at the point-of-care for molecular diagnostics

ET Laryea, JH Nichols - Expert Review of Molecular Diagnostics, 2024 - Taylor & Francis
Introduction Faster turnaround times can lead to rapid patient treatment. Implementing a
point-of-care (POC) molecular COVID-19 test requires careful planning. In the POC setting …

Best practices in qPCR and dPCR validation in regulated bioanalytical laboratories

A Hays, R Islam, K Matys, D Williams - The AAPS journal, 2022 - Springer
The use of molecular techniques in the bioanalytical laboratory is becoming more common
as the number of gene and cell therapy products continues to increase. Currently, there is no …

Fate of Sniff-the-Diseases Through Nanomaterials-Supported Optical Biochip Sensors

BA Taha, V Chaudhary, S Rustagi… - ECS Journal of Solid …, 2024 - iopscience.iop.org
Early diagnosis through noninvasive tools is a cornerstone in the realm of personalized and
medical healthcare, averting direct/indirect infection transmission and directly influencing …

Repeat testing of mpox specimens with late CTs improves detection of potential false positive cases

RC Shean, WC Hymas, J Klein, M Pyne… - Journal of Clinical …, 2024 - Am Soc Microbiol
The mpox pandemic necessitated the rapid development of clinical assays for monkeypox
virus detection. While the majority of mpox specimens have high viral loads with …

Comprehensive analysis and human health risk assessment of tap water quality in Dhaka City, Bangladesh: Integrating source identification, index-based evaluation …

TN Ariyan, SB Quraishi, MNE Alam, MSR Khan… - Journal of Hazardous …, 2025 - Elsevier
Despite potential contamination, tap water remains the primary source of drinking in
megacities. However, the sources of heavy metal (oid) s contamination and associated …

[HTML][HTML] Molecular genetics testing

C Ishida, M Zubair, V Gupta - 2020 - europepmc.org
Objectives: Describe the types of genetic molecular testing. Explain the procedures and
indications of genetic molecular testing. Review the normal and critical findings of genetic …

Evolution of Minimally Invasive and Non-Invasive Preimplantation Genetic Testing: An Overview

E Moustakli, A Zikopoulos, C Skentou, I Bouba… - Journal of Clinical …, 2024 - mdpi.com
Preimplantation genetic testing (PGT) has become a common supplementary
diagnοstic/testing tοol for in vitro fertilization (ΙVF) cycles due to a significant increase in …

Implementation of an ISO 15189 accredited next generation sequencing service for cell-free total nucleic acid (cfTNA) analysis to facilitate driver mutation reporting in …

R Werner, R Crosbie, M Dorney, A Connolly… - Journal of Clinical …, 2024 - jcp.bmj.com
Aims Next generation sequencing (NGS) on tumour tissue is integral to the delivery of
personalised medicine and targeted therapy. NGS on liquid biopsy, a much less invasive …