[HTML][HTML] Hypoxia-induced up-regulation of VASP promotes invasiveness and metastasis of hepatocellular carcinoma

Z Liu, Y Wang, C Dou, M Xu, L Sun, L Wang, B Yao… - Theranostics, 2018 - ncbi.nlm.nih.gov
Rational: Patients with hepatocellular carcinoma (HCC) have a poor prognosis mostly due to
intrahepatic as well as distal metastasis. Vasodilator-stimulated phosphoprotein (VASP), a …

Risk of solid cancer in patients exposed to anti-tumour necrosis factor therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid …

LK Mercer, M Lunt, ALS Low, WG Dixon… - Annals of the rheumatic …, 2015 - Elsevier
Background Patients with rheumatoid arthritis (RA) have an increased risk of certain solid
cancers, in particular lung cancer, compared to the general population. Treatment with …

Tumor necrosis factor-α, a regulator and therapeutic agent on breast cancer

D Liu, X Wang, Z Chen - Current pharmaceutical biotechnology, 2016 - ingentaconnect.com
The cell-mediated immunity and cytotoxic agents play a significant role on tumor cell
apoptosis. Tumor necrosis factor-α (TNF-α) is an intricate linker between inflammation and …

The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer

K Li, J Zhang, Y Tian, Y He, X Xu, W Pan, Y Gao… - Oncogene, 2020 - nature.com
Previous studies have shown that the main function of VASP is to regulate the cytoskeleton
and play an important role in promoting tumor cell metastasis. In this study, we first reveal …

ITGA3 interacts with VASP to regulate stemness and epithelial-mesenchymal transition of breast cancer cells

H Zhang, X Cui, X Li, L Li - Gene, 2020 - Elsevier
Background The interaction of integrin and extracellular matrix (ECM) has a profound
implication on pathological conditions such as tumor growth and infiltration. Related reports …

TNF-α mediated increase of HIF-1α inhibits VASP expression, which reduces alveolar-capillary barrier function during acute lung injury (ALI)

M Tang, Y Tian, D Li, J Lv, Q Li, C Kuang, P Hu… - PloS one, 2014 - journals.plos.org
Acute lung injury (ALI) is an inflammatory disorder associated with reduced alveolar-
capillary barrier function and increased pulmonary vascular permeability. Vasodilator …

The role of vasodilator-stimulated phosphoproteins in the development of malignant tumors

J Gui, H Zhou, H Wan, D Yang, Q Liu… - Current Cancer Drug …, 2024 - benthamdirect.com
Vasodilator-stimulated phosphoprotein (VASP) is an actin-binding protein that includes
three structural domains: Enabled/VASP homolog1 (EVH1), EVH2, and proline-rich (PRR) …

Inhibitory effect of flavonoid xanthomicrol on triple‐negative breast tumor via regulation of cancer‐associated microRNAs

F Attari, F Keighobadi, M Abdollahi… - Phytotherapy …, 2021 - Wiley Online Library
Breast cancer is the leading cause of cancer death in women worldwide. Due to the side
effects of current chemo‐reagents on healthy tissues, it is essential to search for alternative …

Comprehensive serum proteomics profiles and potential protein biomarkers for the early detection of advanced adenoma and colorectal cancer

C Tan, G Qin, QQ Wang, KM Li… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND The majority of colorectal cancer (CRC) cases develop from precursor
advanced adenoma (AA). With the development of proteomics technologies, blood protein …

Silencing lncRNA SNHG6 suppresses proliferation and invasion of breast cancer cells through miR-26a/VASP axis

K Li, Y Ma, Y Tian, X Xu, Y Gao, Y He, W Pan… - … -Research and Practice, 2019 - Elsevier
The important role of LncRNA in the development of breast cancer is attracting more and
more attention. In the previous study, we found that the expression level of LncRNA SNHG6 …