Nanotransducer-enabled deep-brain neuromodulation with NIR-II light

X Wu, F Yang, S Cai, K Pu, G Hong - ACS nano, 2023 - ACS Publications
The second near-infrared window (NIR-II window), which ranges from 1000 to 1700 nm in
wavelength, exhibits distinctive advantages of reduced light scattering and thus deep …

Near-infrared II fluorescence imaging

EL Schmidt, Z Ou, E Ximendes, H Cui… - Nature Reviews …, 2024 - nature.com
Fluorescence imaging in the second near-infrared (NIR-II) window enables deep-tissue
imaging with high resolution and improved contrast by taking advantage of the reduced light …

Activation of mechanoluminescent nanotransducers by focused ultrasound enables light delivery to deep-seated tissue in vivo

S Jiang, X Wu, F Yang, NJ Rommelfanger, G Hong - Nature Protocols, 2023 - nature.com
Light is used extensively in biological and medical research for optogenetic
neuromodulation, fluorescence imaging, photoactivatable gene editing and light-based …

Purely Organic Fluorescence Afterglow: Visible‐Light‐Excitation, Inherent Mechanism, Tunable Color, and Practical Applications with Very Low Cost

J Wang, Y Yang, K Li, L Zhang… - Angewandte Chemie …, 2023 - Wiley Online Library
Purely organic materials with visible light excitable fluorescence afterglow are promising for
applications. Herein, fluorescence afterglow with various intensity and duration was …

Principles and applications of sono-optogenetics

F Yang, SJ Kim, X Wu, H Cui, SK Hahn… - Advanced drug delivery …, 2023 - Elsevier
Optogenetics has revolutionized neuroscience research through its spatiotemporally precise
activation of specific neurons by illuminating light on opsin-expressing neurons. A long …

Modulating smart mechanoluminescent phosphors for multistimuli responsive optical wood

J Luo, B Ren, X Zhang, M Zhu, T Liang… - Advanced …, 2024 - Wiley Online Library
Mechanoluminescence is a smart light‐emitting phenomenon in which applied mechanical
energy is directly converted into photon emissions. In particular, mechanoluminescent …

Ultrasound-Induced Cascade Amplification in a Mechanoluminescent Nanotransducer for Enhanced Sono-Optogenetic Deep Brain Stimulation

W Wang, KW Kevin Tang, I Pyatnitskiy, X Liu, X Shi… - ACS …, 2023 - ACS Publications
Remote and genetically targeted neuromodulation in the deep brain is important for
understanding and treatment of neurological diseases. Ultrasound-triggered …

Ultrasound-activated luminescence with color tunability enabled by mechanoluminescent colloids and perovskite quantum dots

F Yang, H Cui, X Wu, SJ Kim, G Hong - Nanoscale, 2023 - pubs.rsc.org
Ultrasound represents a wireless and non-contact route for energy delivery and device
control, owing to its ability to propagate and focus in various mediums including biological …

UCNPs-based nanoreactors with ultraviolet radiation-induced effect for enhanced ferroptosis therapy of tumor

K Zhang, J Wang, L Peng, Y Zhang, J Zhang… - Journal of Colloid and …, 2023 - Elsevier
The limitations of light source limit the clinical application of optical therapy technology. How
to improve the application efficiency of radiant light has become the focus of researchers …

Bioinspired nanotransducers for neuromodulation

F Yang, X Wu, S Cai, G Hong - Nano Research, 2024 - Springer
The field of neuromodulation has experienced significant advancements in the past decade,
owing to breakthroughs in disciplines such as materials science, genetics, bioengineering …