Melatonin has been speculated to be mainly synthesized by mitochondria. This speculation
is supported by the recent discovery that aralkylamine N-acetyltransferase/serotonin N …

Mitochondria regulate multiple cell processes, including calcium signaling, apoptosis and
cell metabolism. Mitochondria contain their own circular genome encoding selected …

Platelets are known to enhance the wound-healing activity of mesenchymal stem cells
(MSCs). However, the mechanism by which platelets improve the therapeutic potential of …

Stroke is the leading cause of death and physical disability worldwide. Mitochondrial
dysfunction has been considered as one of the hallmarks of ischemic stroke and contributes …

Recently, we showed that generation of tumours in syngeneic mice by cells devoid of
mitochondrial (mt) DNA (ρ0 cells) is linked to the acquisition of the host mtDNA. However …

Mitochondria (MT) participate in most metabolic activities of mammalian cells. A near-
unidirectional mitochondrial transfer from T cells to cancer cells was recently observed to" …

Background The transfer of whole mitochondria that occurs during cell contact has been
found to support cancer progression. However, the regulatory role of mitochondria alone is …

Mitochondria are major energy-producing organelles that have central roles in cellular
metabolism. They also act as important signalling hubs, and their dynamic regulation in …

Astrocytes are the major glial cell in the central nervous system. These polarized cells
possess numerous processes that ensheath the vasculature and contact synapses …

Cell-to-cell heterogeneity drives a range of (patho) physiologically important phenomena,
such as cell fate and chemotherapeutic resistance. The role of metabolism, and particularly …