The extracellular matrix (ECM) is an integral component of all organs and plays a pivotal
role in tissue homeostasis and repair. While the ECM was long thought to mostly have …

The past decade has seen an explosion of research directed toward better understanding of
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …

Cancer progresses by evading the immune system. Elucidating diverse immune evasion
strategies is a critical step in the search for next-generation immunotherapies for cancer …

Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection represent a major issue in long coronavirus disease. How SARS-CoV-2 …

Astrocytic brain tumours, including glioblastomas, are incurable neoplasms characterized by
diffusely infiltrative growth. Here we show that many tumour cells in astrocytomas extend …

Maternal decidual NK (dNK) cells promote placentation, but how they protect against
placental infection while maintaining fetal tolerance is unclear. Here we show that human …

Interaction of T cell with antigen-bearing dendritic cells (DC) results in T cell activation, but
whether this interaction has physiological consequences on DC function is largely …

Mammalian genes were long thought to be constrained within somatic cells in most cell
types. This concept was challenged recently when cellular organelles including …

Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

Summary Foxp3+ T regulatory (Treg) cells prevent inflammatory disease but the mechanistic
basis of suppression is not understood completely. Gene silencing by RNA interference can …