Therapeutic glucocorticoids have been widely used in rheumatic diseases since they
became available over 60 years ago. Despite the advent of more specific biologic therapies …

For more than 70 years, glucocorticoids (GCs) have been a powerful and affordable
treatment option for inflammatory diseases. However, their benefits do not come without a …

The glucocorticoid receptor (GR) has been shown to be important for mediating cellular
responses to stress and circulating glucocorticoids. Ligand-dependent transcriptional …

Glucocorticoids (GCs) are widely used in tumor therapy to reduce tumor growth,
inflammation, edema, and other side effects. Controversially, GCs may also cause the …

For over 70 years, the unique anti-inflammatory properties of glucocorticoids (GCs), which
mediate their effects via the ligand-activated transcription factor, the glucocorticoid receptor …

Asthma is a chronic inflammatory disease of the airways characterized by shortness of
breath, chest tightness, coughing, and wheezing. For several decades (approximately 30 …

Mounting evidence indicates that adverse intrauterine conditions increase offspring's
hypercholesterolemia susceptibility in adulthood. This study aimed to confirm prenatal …

Background: Glucocorticoids are among the most commonly prescribed drugs, but there is
no biomarker that can quantify their action. The aim of the study was to identify and validate …

Adverse environments during pregnancy can increase susceptibility to chronic diseases in
adult offspring. The occurrence and development of fetal-originated diseases were …

This review showcases miRNAs contributing to the regulation of bone forming osteoblasts
through their effects on the TGFβ and BMP pathways, with a focus on ligands, receptors and …