In recent years, the traditional view of the hemostatic system as being regulated by a
coagulation factor cascade coupled with platelet activation has been increasingly …

Platelets are inflammatory anuclear cells with a well-established role in the development
and manifestation of atherosclerosis. Activated platelets secrete a plethora of chemokines …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emergent pathogen
responsible for the coronavirus disease 2019 (COVID-19). Since its emergence, the novel …

Extracellular vesicles (EVs) compose a heterogenous group of membrane-derived particles,
including exosomes, microvesicles and apoptotic bodies, which are released into the …

Atherosclerosis is the leading cause of death worldwide and leukocyte recruitment is a key
element of this phenomenon, thus allowing immune cells to enter the arterial wall. There, in …

The notion of blood coagulation dates back to the ancient Greek civilization. However, the
emergence of innovative scientific discoveries that started in the seventeenth century …

Platelet-derived large extracellular vesicles (often referred to as microparticles in the field of
cardiovascular disease) have been identified as effector in the atherothrombotic process …

Microparticles (MPs) are small membrane vesicles that are shed from virtually all cells in
response to stress. Widely described in atherothrombotic diseases, recent data suggest a …

Introduction: Blood-recirculating medical devices, such as mechanical circulatory support
(MCS), extracorporeal membrane oxygenators (ECMO), and hemodialyzers, are commonly …

In patients with atrial fibrillation, oral anticoagulation with oral thrombin inhibitors (OTIs), in
contrast to vitamin K antagonists (VKAs), associates with a modest increase in acute …