Blue light stimulation of the blind spot in human: from melanopsin to clinically relevant biomarkers of myopia

A Amorim-de-Sousa, R Chakraborty, MJ Collins… - Bioelectronic …, 2024 - Springer
The protective effects of time spent outdoors emphasize the major role of daylight in myopia.
Based on the pathophysiology of myopia, the impact of blue light stimulation on the …

[HTML][HTML] Choroidal thickness, myopia, and myopia control interventions in children: a Meta-analysis and systemic review

QY Meng, ZQ Miao, ST Liang, X Wu… - International Journal …, 2023 - ncbi.nlm.nih.gov
AIM To investigate changes of choroidal thickness (ChT) in children with myopia and the
effect of current myopia control interventions on ChT. METHODS Major literature databases …

GABAB Receptor Activation Affects Eye Growth in Chickens with Visually Induced Refractive Errors

H Liu, F Schaeffel, Z Yang, MP Feldkaemper - Biomolecules, 2023 - mdpi.com
This study aims to explore the role of GABAB receptors in the development of deprivation
myopia (DM), lens-induced myopia (LIM) and lens-induced hyperopia (LIH). Chicks were …

[HTML][HTML] An Evidence-Based Narrative Review of Scleral Hypoxia Theory in Myopia: From Mechanisms to Treatments

Q Xiao, X Zhang, ZL Chen, YY Zou… - International Journal of …, 2025 - mdpi.com
Myopia is one of the dominant causes of visual impairment in the world. Pathological myopia
could even lead to other serious eye diseases. Researchers have reached a consensus that …

Increase in choroidal thickness after blue light stimulation of the blind spot in young adults

H Hoseini-Yazdi, SA Read, MJ Collins, H Bahmani… - Bioelectronic …, 2024 - Springer
Background Blue light activates melanopsin, a photopigment that is expressed in
intrinsically photosensitive retinal ganglion cells (ipRGCs). The axons of ipRGCs converge …

Choroidal blood perfusion could predict the sensitivity of myopia formation in Guinea pigs

Y Yang, M Chen, X Yao, J Wang, J Shi, Y Wang… - Experimental Eye …, 2023 - Elsevier
In this study, we explored the predictive role of choroidal blood perfusion (ChBP) and
choroidal thickness (ChT) on the development of myopia in guinea pigs. Optical Coherence …

The potential role of amino acids in myopia: inspiration from metabolomics

Y Xie, L Zhang, S Chen, C Xie, J Tong, Y Shen - Metabolomics, 2025 - Springer
Background Due to the high prevalence of myopia, there is a growing need for the
identification of myopia intervention mechanisms and targets. Metabolomics has been …

[HTML][HTML] Mechanisms of emmetropization and what might go wrong in myopia

F Schaeffel, B Swiatczak - Vision Research, 2024 - Elsevier
Studies in animal models and humans have shown that refractive state is optimized during
postnatal development by a closed-loop negative feedback system that uses retinal image …

Effects of computer-generated patterns with different temporal and spatial frequencies on choroidal thickness, retinal dopamine and candidate genes in chickens …

H Liu, F Schaeffel, MP Feldkaemper - Frontiers in Medicine, 2024 - frontiersin.org
Purpose Changes in choroidal thickness (ChT) are proposed to predict myopia development
but evidence is mixed. We investigated time courses of choroidal responses, following …

Advances in the study of the influence of photoreceptors on the development of myopia

K Wang, G Han, R Hao - Experimental Eye Research, 2024 - Elsevier
This review examines the pivotal role of photoreceptor cells in ocular refraction
development, focusing on dopamine (DA) as a key neurotransmitter. Contrary to the earlier …