New isoindole‐1, 3‐dione substituted sulfonamides as potent inhibitors of carbonic anhydrase and acetylcholinesterase: Design, synthesis, and biological evaluation
Herein, a series of isoindole‐1, 3‐dione substituted sulfonamide derivatives (3, 4 a–k) were
designed, synthesized, and biologically evaluated, as inhibitors of carbonic anhydrase (CA) …
designed, synthesized, and biologically evaluated, as inhibitors of carbonic anhydrase (CA) …
Synthesis, Antimicrobial, Antiquorum‐Sensing, and Cytotoxic Activities of New Series of Isoindoline‐1,3‐dione, Pyrazolo[5,1‐a]isoindole, and Pyridine Derivatives
NS El‐Gohary, MI Shaaban - Archiv der Pharmazie, 2015 - Wiley Online Library
New series of isoindoline‐1, 3‐diones 2–9, pyrazolo [5, 1‐a] isoindoles 10–14, and
pyridines 16–18 were synthesized. Twenty of the synthesized compounds were screened for …
pyridines 16–18 were synthesized. Twenty of the synthesized compounds were screened for …
Design and synthesis of novel tetrabromophthalimide derivatives as potential tubulin inhibitors endowed with apoptotic induction for cancer treatment
M Abdel‐Motaal, DA Aldakhili… - Drug Development …, 2024 - Wiley Online Library
Although various approaches exist for treating cancer, chemotherapy continues to hold a
prominent role in the management of this disease. Besides, microtubules serve as a vital …
prominent role in the management of this disease. Besides, microtubules serve as a vital …
Synthesis, anti-inflammatory, and antiproliferative activity evaluation of isoindole, pyrrolopyrazine, benzimidazoisoindole, and benzimidazopyrrolopyrazine derivatives
A number of isoindole (3x, 3y, 6xa–6ye), pyrrolopyrazine (3z, 6za–6ze),
benzimidazoisoindole (4x, 4y, 7xa–7ye), and benzimidazopyrrolopyrazine (4z, 7za–7ze) …
benzimidazoisoindole (4x, 4y, 7xa–7ye), and benzimidazopyrrolopyrazine (4z, 7za–7ze) …
Isoindoline derivatives of α‐amino acids as cyclooxygenase 1 and 2 inhibitors
T Mancilla‐Percino, CR Trejo‐Muñoz… - Archiv der …, 2016 - Wiley Online Library
IC50 values were obtained for two series of isoindolines derived from α‐amino acids over
cyclooxygenase 1 and 2 (COX‐1 and COX‐2). In order to explain the biological activity …
cyclooxygenase 1 and 2 (COX‐1 and COX‐2). In order to explain the biological activity …
Anti-inflammatory aminoacetylenic isoindoline-1, 3-dione derivatives modulate cytokines production from different spleen cell populations
We recently designed a series of N-[4-(t-amino-yl)-but-2-yn-1-yl] isoindoline-1, 3-diones as
anti-inflammatory compounds, called ZM compounds. These ZM compounds were …
anti-inflammatory compounds, called ZM compounds. These ZM compounds were …
Analgesic and Toxicity Studies of Aminoacetylenic Isoindoline‐1, 3‐dione Derivatives
R Shakir, ZA Muhi-Eldeen, KZ Matalka… - International …, 2012 - Wiley Online Library
We have developed a series of aminoacetylenic isoindoline‐1, 3‐dione compounds and
showed their anti‐inflammatory activities by reducing carrageenan‐induced rat paw edema …
showed their anti‐inflammatory activities by reducing carrageenan‐induced rat paw edema …
A Garratt-Braverman route to isoindolines and phthalans
Abstract Garratt-Braverman (GB) cyclization, two Csingle bondC bond forming reaction in a
single step, has been utilized to construct several isoindoline and phthalan derivatives. The …
single step, has been utilized to construct several isoindoline and phthalan derivatives. The …
Grinding and Microwave‐assisted Synthesis of Heterocyclic Molecules in High Yields and Their Biological Evaluation
Cis‐cyclohexane1, 2‐dicarboxylic acid (1a), phthalic acid (1b), and pyrazine 2, 3‐
dicarboxylic acid (1c) on grinding with hydrazine hydrate (2a) gave 2‐aminohexahydro‐1H …
dicarboxylic acid (1c) on grinding with hydrazine hydrate (2a) gave 2‐aminohexahydro‐1H …
Estrategias de desplazamiento de Ateles geoffroyi yucatanensis y Alouatta pigra en la búsqueda de recursos tróficos durante la temporada seca y húmeda en la …
M en Neuroetología - 2013 - sii.ecosur.mx
UNIVERSIDAD VERACRUZANA Instituto de Neuroetología Estrategias de desplazamiento de
Ateles geoffroyi yucatanensis y Alouatta pi Page 1 UNIVERSIDAD VERACRUZANA Instituto …
Ateles geoffroyi yucatanensis y Alouatta pi Page 1 UNIVERSIDAD VERACRUZANA Instituto …