Nanoparticle vaccines against infectious diseases

R Pati, M Shevtsov, A Sonawane - Frontiers in immunology, 2018 - frontiersin.org
Due to emergence of new variants of pathogenic micro-organisms the treatment and
immunization of infectious diseases have become a great challenge in the past few years. In …

Advanced liposome and polymersome-based drug delivery systems: Considerations for physicochemical properties, targeting strategies and stimuli-sensitive …

S Kansız, YM Elçin - Advances in Colloid and Interface Science, 2023 - Elsevier
Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …

[HTML][HTML] Nanoparticle vaccines

L Zhao, A Seth, N Wibowo, CX Zhao, N Mitter, C Yu… - Vaccine, 2014 - Elsevier
Nanotechnology increasingly plays a significant role in vaccine development. As vaccine
development orientates toward less immunogenic “minimalist” compositions, formulations …

Intradermal and transdermal drug delivery using microneedles–Fabrication, performance evaluation and application to lymphatic delivery

AH Sabri, Y Kim, M Marlow, DJ Scurr, J Segal… - Advanced drug delivery …, 2020 - Elsevier
The progress in microneedle research is evidenced by the transition from simple 'poke and
patch'solid microneedles fabricated from silicon and stainless steel to the development of …

Virus-like particle vaccines: immunology and formulation for clinical translation

B Donaldson, Z Lateef, GF Walker… - Expert review of …, 2018 - Taylor & Francis
Introduction: Virus-like particle (VLP) vaccines face significant challenges in their translation
from laboratory models, to routine clinical administration. While some VLP vaccines thrive …

Materials engineering for immunomodulation

JA Hubbell, SN Thomas, MA Swartz - Nature, 2009 - nature.com
The engineering of materials that can modulate the immune system is an emerging field that
is developing alongside immunology. For therapeutic ends such as vaccine development …

Bacterial superglue enables easy development of efficient virus-like particle based vaccines

S Thrane, CM Janitzek, S Matondo, M Resende… - Journal of …, 2016 - Springer
Abstract Background Virus-like particles (VLPs) represent a significant advance in the
development of subunit vaccines, combining high safety and efficacy. Their particulate …

Immunostimulatory polymers as adjuvants, immunotherapies, and delivery systems

AM Weiss, S Hossainy, SJ Rowan, JA Hubbell… - …, 2022 - ACS Publications
Activating innate immunity in a controlled manner is necessary for the development of next-
generation therapeutics. Adjuvants, or molecules that modulate the immune response, are …

[HTML][HTML] Breast cancer vaccines: New insights into immunomodulatory and nano-therapeutic approaches

F Davodabadi, M Sarhadi, J Arabpour, S Sargazi… - Journal of Controlled …, 2022 - Elsevier
Breast cancer (BC) is known to be a highly heterogeneous disease that is clinically
subdivided into four primary molecular subtypes, each having distinct morphology and …

Improvement of different vaccine delivery systems for cancer therapy

A Bolhassani, S Safaiyan, S Rafati - Molecular cancer, 2011 - Springer
Cancer vaccines are the promising tools in the hands of the clinical oncologist. Many tumor-
associated antigens are excellent targets for immune therapy and vaccine design. Optimally …