HIV-1 integrase strand transfer inhibitors and neurodevelopment

EG Foster, HE Gendelman, AN Bade - Pharmaceuticals, 2022 - mdpi.com
Children born to mothers, with or at risk, of human immunodeficiency virus type-1 (HIV-1)
infection are on the rise due to affordable access of antiretroviral therapy (ART) to pregnant …

Weight and Metabolic Outcomes in Naïve HIV Patients Treated with Integrase Inhibitor-Based Antiretroviral Therapy: A Systematic Review and Meta-Analysis

G Valenzuela-Rodriguez, C Diaz-Arocutipa… - Journal of Clinical …, 2023 - mdpi.com
Background: The use of integrase inhibitor-based antiretroviral therapy could be associated
with worse weight and metabolic outcomes in patients with HIV infection. Methods: PubMed …

Real-life experience on dolutegravir and lamivudine as initial or switch therapy in a silver population living with HIV

M Mazzitelli, L Sasset, S Gardin, D Leoni, M Trunfio… - Viruses, 2023 - mdpi.com
Background: Clinical trials and real-life studies have granted the efficacy and safety of
dolutegravir and lamivudine (DTG/3TC) in naïve and experienced people living with HIV …

Association between weight gain and the incidence of cardiometabolic conditions among people living with HIV-1 at high risk of weight gain initiated on antiretroviral …

GA McComsey, B Emond, A Shah, BK Bookhart… - Infectious Diseases and …, 2022 - Springer
Introduction Antiretroviral therapy (ART) has been associated with weight gain in people
living with HIV-1 (PLWH); however, limited research has assessed whether early weight …

[图书][B] Pharmacology Research And Textbook 2: HIV-1 Integrase Inhibitors, Coenzyme Q10, and Ferroptosis

AT Mohammadi, R Nouralizadeh, N Naghsh, S Abbasi… - books.google.com
Page 1 Pharmacology Research And Textbook 2 Chapter1: HIV-1 Integrase Inhibitors and
Neurodevelopment Chapter2: Coenzyme Q10 Chapter3: Ferroptosis Author in Chief …

A clinical review of HIV integrase strand transfer inhibitors (INSTIs) for the prevention and treatment of HIV-1 infection

AV Zhao, RD Crutchley, RC Guduru, K Ton, T Lam… - Retrovirology, 2022 - Springer
Integrase strand transfer inhibitors (INSTIs) have improved the treatment of human
immunodeficiency virus (HIV). There are currently four approved for use in treatment-naïve …

Clinical characteristics of women with HIV in the RESPOND cohort: A descriptive analysis and comparison to men

J Hutchinson, B Neesgard, J Kowalska… - HIV …, 2024 - Wiley Online Library
Background Women with HIV are globally underrepresented in clinical research. Existing
studies often focus on reproductive outcomes, seldom focus on older women, and are often …

Re-evaluating the relationship between youth with HIV and BMI in an age of increasing rates of overweight and obese youth

SV Hill, J Hao, M Newlin-Bradner, DM Long… - BMC Research …, 2024 - Springer
Background Newer antiretrivirals (ART) have shifted the metabolic experiences of people
with HIV (PWH) from those of wasting syndrome to increases in body mass index (BMI). This …

Management of Integrase Inhibitor-Associated Weight Gain: A Practical Clinical Approach

BR Wood - Current Infectious Disease Reports, 2023 - Springer
Abstract Purpose of Review The purpose of this review is to outline a practical clinical
approach to monitoring and managing integrase strand transfer inhibitor (INSTI)-associated …

Weight gain in HIV-infected patients.

AP Rodríguez, I Serrano Lillo, CS González… - AIDS …, 2023 - search.ebscohost.com
Since its emergence, HIV has been linked to metabolic alterations with an impact on the
distribution of fat and the weight of people living with HIV. While extreme weight loss and …