Cerebellar dysfunction in multiple sclerosis

A Wilkins - Frontiers in neurology, 2017 - frontiersin.org
Multiple sclerosis (MS) commonly affects the cerebellum causing acute and chronic
symptoms. Cerebellar signs contribute significantly to clinical disability, and symptoms such …

Behavioural phenotypes in the cuprizone model of central nervous system demyelination

MK Sen, DA Mahns, JR Coorssen… - … & Biobehavioral Reviews, 2019 - Elsevier
The feeding of cuprizone (CPZ) to animals has been extensively used to model the
processes of demyelination and remyelination, with many papers adopting a narrative linked …

The S ymbol D igit M odalities T est as sentinel test for cognitive impairment in multiple sclerosis

J Van Schependom, MB D'hooghe… - European journal of …, 2014 - Wiley Online Library
Background and purpose Cognitive impairment (CI) is found in about half of the multiple
sclerosis (MS) population and is an important contributor to employment status and social …

CSF Parvalbumin levels at multiple sclerosis diagnosis Predict future worse cognition, physical disability, fatigue, and gray matter damage

S Ziccardi, A Tamanti, C Ruggieri… - Neurology …, 2024 - neurology.org
Background and Objectives Cognitive impairment (CI) in multiple sclerosis (MS) is frequent
and determined by a complex interplay between inflammatory and neurodegenerative …

Symptom interconnectivity in multiple sclerosis: a narrative review of potential underlying biological disease processes

T Chitnis, J Vandercappellen, M King… - Neurology and Therapy, 2022 - Springer
Introduction Fatigue, cognitive impairment, depression, and pain are highly prevalent
symptoms in multiple sclerosis (MS). These often co-occur and may be explained by a …

Central fatigue in multiple sclerosis: a review of the literature

P Newland, A Starkweather… - The journal of spinal cord …, 2016 - Taylor & Francis
Concept: Fatigue is a major concern for patients with multiple sclerosis (MS). A clear
definition of MS-related fatigue is a prerequisite for appropriate instruments for fatigue …

Attention and processing speed performance in multiple sclerosis is mostly related to thalamic volume

A Bisecco, S Stamenova, G Caiazzo… - Brain imaging and …, 2018 - Springer
Cognitive impairment (CI), mainly involving attention and processing speed (A-PS), is a
common and disabling symptom in multiple sclerosis (MS). Symbol Digit Modalities Test …

Cerebellar contribution to motor and cognitive performance in multiple sclerosis: an MRI sub-regional volumetric analysis

A D'Ambrosio, E Pagani, GC Riccitelli… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Objective: To investigate the role of cerebellar sub-regions on motor and cognitive
performance in multiple sclerosis (MS) patients. Methods: Whole and sub-regional …

Volumetric brain loss correlates with a relapsing MOGAD disease course

A Rechtman, L Brill, O Zveik, B Uliel, N Haham… - Frontiers in …, 2022 - frontiersin.org
Background Myelin oligodendrocyte glycoprotein antibody disorders (MOGAD) have
evolved as a distinct group of inflammatory, demyelinating diseases of the CNS. MOGAD …

The role of the cerebellum in multiple sclerosis—150 years after Charcot

K Parmar, C Stadelmann, MA Rocca, D Langdon… - Neuroscience & …, 2018 - Elsevier
Despite its functional importance and well known clinical impact in Multiple Sclerosis (MS),
the cerebellum has only received significant attention over the past few years. It is now …