Current (high throughput omics-based) data support the model that human (malignant) germ
cell tumors are not initiated by somatic mutations, but, instead through a defined locked …

Objectives To evaluate whether a computed tomography (CT) radiomics–based machine
learning classifier can predict histopathology of lymph nodes (LNs) after post-chemotherapy …

Liquid biopsies constitute a minimally invasive means of managing cancer patients,
entailing early diagnosis, follow-up and prediction of response to therapy. Their use in the …

Purpose Ejaculatory dysfunction secondary to retrograde ejaculation or anejaculation is a
complication of retroperitoneal lymph node dissection (RPLND) for survivors of testicular …

Methods A multidisciplinary group of Canadian testicular cancer experts (nine medical
oncologists, five uro-oncologists, two radiation oncologists, one genitourinary pathologist …

Background To identify a combination of microRNAs (miRNA) to differentiate between viable
tumor (V) or teratoma (T) and necrosis/fibrosis (N) in pcRPLND specimens of metastatic …

Background Retroperitoneal lymph node dissection (RPLND) is essential for the treatment of
metastatic germ cell tumours of the testis. Recommendations on the referral and …

Simple Summary Testicular germ cell tumours (TGCTs) are the most common type of solid
cancer in men under the age of 40. Of metastases from TGCTs, 95% involve the ipsilateral …

Background Radiological evaluation of postchemotherapy residual masses of metastatic
seminoma is characterized by poor diagnostic accuracy. Serum levels of microRNA-371a-3p …

Advances in risk stratification and therapy enable personalized de-escalation approaches
for oligometastatic testicular cancer, optimizing survivorship. Upfront RPLND, reassessing …