One of the biggest health challenges of today's world is the emergence of antimicrobial
resistance (AMR), which renders conventional therapeutics insufficient and urgently …

This review summarizes studies evaluating the performance of the QuantiFERON-TB Gold
Plus (QFT-Plus) interferon-gamma release assay (IGRA) test for Mycobacterium tuberculosis …

Background The immunologic correlates of risk of Mycobacterium tuberculosis (Mtb)
infection after BCG vaccination are unknown. The mechanism by which BCG influences the …

Background Isoniazid preventive therapy (IPT) decreases risk of tuberculosis (TB) disease;
impact on long-term infant growth is unknown. In a recent randomized trial (RCT), we …

Background Human immunodeficiency virus (HIV)–exposed uninfected (HEU) infants in
endemic settings are at high risk of tuberculosis (TB). For infants, progression from primary …

Background: The effect of maternal HIV on infant Mycobacterium tuberculosis (Mtb) infection
risk is not well-characterized. Methods: Pregnant women with/without HIV and their infants …

Background: HIV-exposed uninfected (HEU) infants have increased risk of tuberculosis (TB).
Testing for Mycobacterium tuberculosis (Mtb) infection is limited by reduced Quantiferon …

Objective To investigate the clinical efficacy of dexamethasone (Dex) combined with
isoniazid in tuberculous meningitis (TBM) and its effect on peripheral blood T cell subsets …

Cumulative 24-month Mycobacterium tuberculosis infection incidence (measured primarily
by tuberculin skin test [TST]) was high among human immunodeficiency virus exposed but …

The study aimed at identifying the determinants of tuberculosis infection among human
immunodeficiency virus (HIV) positive adolescents and subsequently develop a prevention …