The maintenance of mitochondrial DNA integrity—critical analysis and update

M Alexeyev, I Shokolenko… - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
DNA molecules in mitochondria, just like those in the nucleus of eukaryotic cells, are
constantly damaged by noxious agents. Eukaryotic cells have developed efficient …

Magnesium is a key player in neuronal maturation and neuropathology

R Yamanaka, Y Shindo, K Oka - International journal of molecular …, 2019 - mdpi.com
Magnesium (Mg) is the second most abundant cation in mammalian cells, and it is essential
for numerous cellular processes including enzymatic reactions, ion channel functions …

Is there more to aging than mitochondrial DNA and reactive oxygen species?

MF Alexeyev - The FEBS journal, 2009 - Wiley Online Library
With the aging of the population, we are seeing a global increase in the prevalence of age‐
related disorders, especially in developed countries. Chronic diseases disproportionately …

[HTML][HTML] The short-lived African turquoise killifish: an emerging experimental model for ageing

Y Kim, HG Nam, DR Valenzano - Disease models & …, 2016 - journals.biologists.com
Human ageing is a fundamental biological process that leads to functional decay, increased
risk for various diseases and, ultimately, death. Some of the basic biological mechanisms …

A preliminary mitochondrial genome phylogeny of Orthoptera (Insecta) and approaches to maximizing phylogenetic signal found within mitochondrial genome data

JD Fenn, H Song, SL Cameron, MF Whiting - Molecular Phylogenetics and …, 2008 - Elsevier
The phylogenetic utility of mitochondrial genomes (mtgenomes) is examined using the
framework of a preliminary phylogeny of Orthoptera. This study presents five newly …

Mitochondrial oxidative phosphorylation defect in the heart of subjects with coronary artery disease

K Ait-Aissa, SC Blaszak, G Beutner, SW Tsaih… - Scientific reports, 2019 - nature.com
Coronary artery disease (CAD) is a leading cause of death worldwide and frequently
associated with mitochondrial dysfunction. Detailed understanding of abnormalities in …

[图书][B] Clonality: the genetics, ecology, and evolution of sexual abstinence in vertebrate animals

J Avise - 2008 - books.google.com
Approximately 99.9% of vertebrate species reproduce sexually. The exceptional 0.1%
reproduce via asexual or clonal means, which vary wildly and are fascinating in their own …

[HTML][HTML] Aging: A mitochondrial DNA perspective, critical analysis and an update

IN Shokolenko, GL Wilson… - World journal of …, 2014 - ncbi.nlm.nih.gov
The mitochondrial theory of aging, a mainstream theory of aging which once included
accumulation of mitochondrial DNA (mtDNA) damage by reactive oxygen species (ROS) as …

Novel mitochondrial genome rearrangements including duplications and extensive heteroplasmy could underlie temperature adaptations in Antarctic notothenioid …

BF Minhas, EA Beck, CHC Cheng, J Catchen - Scientific reports, 2023 - nature.com
Mitochondrial genomes are known for their compact size and conserved gene order,
however, recent studies employing long-read sequencing technologies have revealed the …

Rearrangement and evolution of mitochondrial genomes in parrots

JR Eberhard, TF Wright - Molecular phylogenetics and evolution, 2016 - Elsevier
Mitochondrial genome rearrangements that result in control region duplication have been
described for a variety of birds, but the mechanisms leading to their appearance and …