Most patients diagnosed with head and neck squamous cell carcinoma (HNSCC) will
present with locally advanced disease, requiring multimodality therapy. While this approach …

Technological advances and clinical research over the past few decades have given
radiation oncologists the capability to personalize treatments for accurate delivery of …

The treatment of cancer with proton radiation therapy was first suggested in 1946 followed
by the first treatments in the 1950s. As of 2020, almost 200 000 patients have been treated …

Radiotherapy (RT) is used to treat approximately 80% of patients with cancer of the head
and neck. Despite enormous advances in RT planning and delivery, a significant number of …

In the Netherlands, the model-based approach is used to identify patients with head and
neck cancer who may benefit most from proton therapy in terms of prevention of late …

Abstract Purpose In the Netherlands, head and neck cancer (HNC) patients qualify for
intensity modulated proton therapy (IMPT) based on model-based selection (MBS). The aim …

Purpose Reducing dose to normal tissues is the advantage of protons versus photons. We
aimed to describe a method for translating this reduction into a clinically relevant benefit …

Radiotherapy (radiation therapy) is one of the main treatments for cancer. The aim is to
deliver a prescribed radiation dose to the tumor, while keeping the unavoidable dose to the …

Objectives Assessment of long term (10-years+) swallowing function, mouth opening, and
quality of life (QoL) in head and neck cancer (HNC) patients treated with chemo …

The favorable beam properties of protons can be translated into clinical benefits by target
dose escalation to improve local control without enhancing unacceptable radiation toxicity or …