Impacts of ecology, parasite antigenic variation, and human genetics on RTS, S/AS01e malaria vaccine efficacy
Abstract Purpose of Review Global malaria elimination has little chance of success without
an effective vaccine. The first malaria vaccine, RTS, S/AS01e, demonstrated moderate …
an effective vaccine. The first malaria vaccine, RTS, S/AS01e, demonstrated moderate …
Impact of high human genetic diversity in Africa on immunogenicity and efficacy of RTS, S/AS01 vaccine
In modern medicine, vaccination is one of the most effective public health strategies to
prevent infectious diseases. Indisputably, vaccines have saved millions of lives by reducing …
prevent infectious diseases. Indisputably, vaccines have saved millions of lives by reducing …
Malaria transmission intensity likely modifies RTS, S/AS01 efficacy due to a rebound effect in Ghana, Malawi, and Gabon
Abstract Background RTS, S/AS01 is the first malaria vaccine to be approved and
recommended for widespread implementation by the World Health Organization (WHO) …
recommended for widespread implementation by the World Health Organization (WHO) …
Tracking immunization coverage, dropout and equity gaps among children ages 12–23 months in Malawi–bottleneck analysis of the Malawi Demographic and Health …
K Mmanga, TE Mwenyenkulu, O Nkoka… - International …, 2022 - academic.oup.com
Background Between 2010 and 2016, the proportion of children 12–23 months of age who
received full immunization in Malawi decreased from 81% to 76%. Most studies on …
received full immunization in Malawi decreased from 81% to 76%. Most studies on …
Epitope-coated polymer particles elicit neutralising antibodies against Plasmodium falciparum sporozoites
Abstract The current Malaria RTS, S vaccine is based on virus-like particles (VLPs)
comprising the NANP repetitive epitopes from the cicumsporozoite protein (CSP) of …
comprising the NANP repetitive epitopes from the cicumsporozoite protein (CSP) of …
Alum pickering emulsion as effective adjuvant to improve malaria vaccine efficacy
Q Chen, N Wu, Y Gao, X Wang, J Wu, G Ma - Vaccines, 2021 - mdpi.com
Malaria is a life-threatening global epidemic disease and has caused more than 400,000
deaths in 2019. To control and prevent malaria, the development of a vaccine is a potential …
deaths in 2019. To control and prevent malaria, the development of a vaccine is a potential …
Barriers and facilitators to nationwide implementation of the malaria vaccine in Ghana
Interventions such as antimalarial drugs, bed nets and insecticides have helped curb the
burden of malaria in the past decade, yet malaria remains a leading cause of morbidity and …
burden of malaria in the past decade, yet malaria remains a leading cause of morbidity and …
A systematic review on malaria and Tuberculosis (TB) vaccine challenges in sub-Saharan African clinical trials
MA Hamisi, NAM Asri, ASM Yassim, R Suppian - PloS one, 2025 - journals.plos.org
Objective For more than a century, developing novel and effective vaccines against malaria
and Tuberculosis (TB) infections has been a challenge. This review sought to investigate the …
and Tuberculosis (TB) infections has been a challenge. This review sought to investigate the …
Pediatric cerebral malaria
G Guenther, D Muller, D Moyo, D Postels - Current tropical medicine …, 2021 - Springer
Abstract Purpose of Review Malaria is the most important parasitic disease of humankind.
Cerebral malaria is malaria's deadliest clinical manifestation and has a profound public …
Cerebral malaria is malaria's deadliest clinical manifestation and has a profound public …
Multifaceted applications of genetically modified micro-organisms: a biotechnological revolution
V Basarkar, S Govardhane… - Current Pharmaceutical …, 2022 - ingentaconnect.com
Background: Genetically modified micro-organisms like bacteria, viruses, algae and fungi
are novel approaches used in the field of healthcare due to better efficacy and targeted …
are novel approaches used in the field of healthcare due to better efficacy and targeted …