Approaching the catalytic mechanism of protein lysine methyltransferases by biochemical and simulation techniques
Protein lysine methyltransferases (PKMTs) transfer up to three methyl groups to the side
chains of lysine residues in proteins and fulfill important regulatory functions by controlling …
chains of lysine residues in proteins and fulfill important regulatory functions by controlling …
Structure, activity and function of the Suv39h1 and Suv39h2 protein lysine methyltransferases
SUV39H1 and SUV39H2 were the first protein lysine methyltransferases that were identified
more than 20 years ago. Both enzymes introduce di-and trimethylation at histone H3 lysine 9 …
more than 20 years ago. Both enzymes introduce di-and trimethylation at histone H3 lysine 9 …
The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation
Protein lysine methyltransferases (PKMTs) play essential roles in gene expression
regulation and cancer development. Somatic mutations in PKMTs are frequently observed in …
regulation and cancer development. Somatic mutations in PKMTs are frequently observed in …
Discovery of NSD2 non-histone substrates and design of a super-substrate
The human protein lysine methyltransferase NSD2 catalyzes dimethylation at H3K36. It has
very important roles in development and disease but many mechanistic features and its full …
very important roles in development and disease but many mechanistic features and its full …
Editorial of Special Issue “Protein Post-Translational Modifications in Signal Transduction and Diseases”
C D'Amore, M Salvi - International Journal of Molecular Sciences, 2021 - mdpi.com
The making of a protein is based on the combination of 20 different monomers (22
considering selenocysteine and pyrrolysine, the latest present only in some archaea and …
considering selenocysteine and pyrrolysine, the latest present only in some archaea and …
[图书][B] Novel Modalities of Gene Regulation Engineering for Eukaryotic Synthetic Biology
J Lee - 2021 - search.proquest.com
Synthetic Biology is the engineering of biological systems to better understand principles of
native biology as well as to impart new and useful functions that could have societal benefit …
native biology as well as to impart new and useful functions that could have societal benefit …