M Desgres, P Menasche - Cell Stem Cell, 2019 - cell.com
Although the clinical outcomes of cell therapy trials have not met initial expectations, emerging evidence suggests that injury-mediated tissue damage might benefit from the …
Human iPSC-derived cardiomyocytes (hiPSC-CMs) have proven invaluable for cardiac disease modeling and regeneration. Challenges with quality, inter-batch consistency …
Y Horikoshi, Y Yan, M Terashvili, C Wells, H Horikoshi… - Cells, 2019 - mdpi.com
Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (CMs)(iPSC-CMs) are a promising cell source for myocardial regeneration, disease modeling and drug …
Despite significant efforts in the study of cardiovascular diseases (CVDs), they persist as the leading cause of mortality worldwide. Considerable research into human pluripotent stem …
Cardiovascular diseases (CVDs) are the leading causes of mortality globally that demand the application of tissue engineering strategies to repair damaged tissues. Conventional …
N Harlaar, SO Dekker, J Zhang, RR Snabel… - Nature Biomedical …, 2022 - nature.com
The lack of a scalable and robust source of well-differentiated human atrial myocytes constrains the development of in vitro models of atrial fibrillation (AF). Here we show that …
Y Song, H Wang, F Yue, Q Lv, B Cai… - Advanced …, 2020 - Wiley Online Library
Cardiovascular diseases are one of the leading causes of death globally. Among various cardiovascular diseases, myocardial infarction is an important one. Compared with …
H Lemcke, N Voronina, G Steinhoff… - Stem Cells …, 2018 - Wiley Online Library
During the past decades, stem cell‐based therapy has acquired a promising role in regenerative medicine. The application of novel cell therapeutics for the treatment of …
Tissue engineering has paved the way for the development of artificial human cardiac muscle patches (hCMPs) and cardiac tissue analogs, especially for treating Myocardial …