M Chaker-Margot, J Barandun, M Hunziker, S Klinge - Science, 2017 - science.org
INTRODUCTION The eukaryotic ribosome is assembled through an intricate process that involves in excess of 250 nonribosomal proteins and small nucleolar RNAs (snoRNAs) …
The assembly of eukaryotic ribosomes follows an assembly line-like pathway in which numerous trans-acting biogenesis factors act on discrete pre-ribosomal intermediates to …
During vertebrate craniofacial development, neural crest cells (NCCs) contribute to most of the craniofacial pharyngeal skeleton. Defects in NCC specification, migration and …
The first metastable assembly intermediate of the eukaryotic ribosomal small subunit (SSU) is the SSU Processome, a large complex of RNA and protein factors that is thought to …
S Zhao, Y Chen, F Chen, D Huang, H Shi… - Nucleic Acids …, 2019 - academic.oup.com
Mpp10 forms a complex with Imp3 and Imp4 that serves as a core component of the ribosomal small subunit (SSU) processome. Mpp10 also interacts with the nucleolar protein …
A Delprato, YA Kadri, N Pérébaskine… - Nucleic acids …, 2014 - academic.oup.com
The essential Rcl1p and Bms1p proteins form a complex required for 40S ribosomal subunit maturation. Bms1p is a GTPase and Rcl1p has been proposed to catalyse the …
K Shimoji, J Jakovljevic, K Tsuchihashi… - Nucleic acids …, 2012 - academic.oup.com
The yeast protein Ebp2 is required for early steps in production of 60S ribosomal subunits. To search for cofactors with which Ebp2 functions, or substrates on which it acts, we …
G Clerget, V Bourguignon-Igel… - Nucleic acids …, 2020 - academic.oup.com
U3 snoRNA and the associated Rrp9/U3-55K protein are essential for 18S rRNA production by the SSU-processome complex. U3 and Rrp9 are required for early pre-rRNA cleavages …
EA Champion, BH Lane, ME Jackrel… - … and cellular biology, 2008 - Am Soc Microbiol
The small subunit (SSU) processome is a ribosome biogenesis intermediate that assembles from its subcomplexes onto the pre-18S rRNA with yet unknown order and structure. Here …