Singular adult neural stem cells do not exist
D Petrik, S Jörgensen, V Eftychidis, FA Siebzehnrubl - Cells, 2022 - mdpi.com
Adult neural stem cells (aNSCs) are the source for the continuous production of new
neurons throughout life. This so-called adult neurogenesis has been extensively studied; the …
neurons throughout life. This so-called adult neurogenesis has been extensively studied; the …
Loss of IRF7 accelerates acute myeloid leukemia progression and induces VCAM1-VLA-4 mediated intracerebral invasion
H Wang, D Zhang, X Cui, Y Dai, C Wang, W Feng, X Lv… - Oncogene, 2022 - nature.com
Abstract Interferon regulatory factor 7 (IRF7) is widely studied in inflammatory models. Its
effects on malignant progression have been documented mainly from the perspective of the …
effects on malignant progression have been documented mainly from the perspective of the …
Apically localized PANX1 impacts neuroepithelial expansion in human cerebral organoids
RJ Noort, H Zhu, RT Flemmer, CS Moore… - Cell Death …, 2024 - nature.com
Dysfunctional paracrine signaling through Pannexin 1 (PANX1) channels is linked to several
adult neurological pathologies and emerging evidence suggests that PANX1 plays an …
adult neurological pathologies and emerging evidence suggests that PANX1 plays an …
Application of Lineage Tracing in Central Nervous System Development and Regeneration
H Li, Y Zhuang, B Zhang, X Xu, B Liu - Molecular Biotechnology, 2024 - Springer
The central nervous system (CNS) is a complicated neural network. The origin and evolution
of functional neurons and glia cells remain unclear, as do the cellular alterations that occur …
of functional neurons and glia cells remain unclear, as do the cellular alterations that occur …
Hippocampal Mitochondrial Transplantation Alleviates Age‐Associated Cognitive Decline via Enhancing Wnt Signaling and Neurogenesis
Z Zhang, D Wei, Z Li, H Guo, Y Wu… - Computational …, 2022 - Wiley Online Library
Gradual cognition decline and mitochondrial dysfunction are two notable changes closely
associated with aging. Enhancing mitochondrial function has been assumed to be antiaging …
associated with aging. Enhancing mitochondrial function has been assumed to be antiaging …
[HTML][HTML] Prdm16 and Vcam1 regulate the postnatal disappearance of embryonic radial glia and the ending of cortical neurogenesis
J Li, MI Godoy, AJ Zhang, G Diamante, IS Ahn… - BioRxiv, 2023 - ncbi.nlm.nih.gov
Embryonic neural stem cells (NSCs, ie, radial glia) in the ventricular-subventricular zone (V-
SVZ) generate the majority of neurons and glia in the forebrain. Postnatally, embryonic …
SVZ) generate the majority of neurons and glia in the forebrain. Postnatally, embryonic …
[HTML][HTML] Dephosphorylation of 4EBP1/2 Induces Prenatal Neural Stem Cell Quiescence
LC Geben, AA Brockman, MBL Chalkley, SR Sweet… - bioRxiv, 2023 - ncbi.nlm.nih.gov
A limiting factor in the regenerative capacity of the adult brain is the abundance and
proliferative ability of neural stem cells (NSCs). Adult NSCs are derived from a …
proliferative ability of neural stem cells (NSCs). Adult NSCs are derived from a …