Control of immunity by glucocorticoids in health and disease

A Shimba, K Ikuta - Seminars in Immunopathology, 2020 - Springer
Animals receive environmental stimuli from neural signals in order to produce hormones that
control immune responses. Glucocorticoids (GCs) are a group of steroid hormones …

Glucocorticoids, sex hormones, and immunity

O Bereshchenko, S Bruscoli, C Riccardi - Frontiers in immunology, 2018 - frontiersin.org
Glucocorticoid hormones regulate essential body functions in mammals, control cell
metabolism, growth, differentiation, and apoptosis. Importantly, they are potent suppressors …

[HTML][HTML] Anti-inflammatory roles of glucocorticoids are mediated by Foxp3+ regulatory T cells via a miR-342-dependent mechanism

D Kim, QT Nguyen, J Lee, SH Lee, A Janocha, S Kim… - Immunity, 2020 - cell.com
Glucocorticoids (GC) are the mainstay treatment option for inflammatory conditions. Despite
the broad usage of GC, the mechanisms by which GC exerts its effects remain elusive. Here …

Revisiting steroidogenesis and its role in immune regulation with the advanced tools and technologies

S Chakraborty, J Pramanik, B Mahata - Genes & Immunity, 2021 - nature.com
Historically tools and technologies facilitated scientific discoveries. Steroid hormone
research is not an exception. Unfortunately, the dramatic advancement of the field faded this …

[HTML][HTML] Changes in physiology and immune system during pregnancy and coronavirus infection: A review

M Chen, J Zeng, X Liu, G Sun, Y Gao, J Liao… - European Journal of …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the 3 rd epidemic
coronavirus after severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle …

Defining the role of glucocorticoids in inflammation

S Ronchetti, G Migliorati, S Bruscoli… - Clinical Science, 2018 - portlandpress.com
An established body of knowledge and clinical practice has argued in favor of the use of
glucocorticoids in various chronic inflammatory and autoimmune diseases. However, the …

Pleiotropic effects of glucocorticoids on the immune system in circadian rhythm and stress

A Shimba, A Ejima, K Ikuta - Frontiers in immunology, 2021 - frontiersin.org
Glucocorticoids (GCs) are a class of steroid hormones secreted from the adrenal cortex.
Their production is controlled by circadian rhythm and stress, the latter of which includes …

Emerging role of IL-35 in inflammatory autoimmune diseases

LC Su, XY Liu, AF Huang, WD Xu - Autoimmunity Reviews, 2018 - Elsevier
Abstract Interleukin 35 (IL-35) is the recently identified member of the IL-12 family of
cytokines and provides the possibility to be a target for new therapies for autoimmune …

Progesterone modulation of pregnancy-related immune responses

NM Shah, N Imami, MR Johnson - Frontiers in immunology, 2018 - frontiersin.org
Progesterone (P4) is an important steroid hormone for the establishment and maintenance
of pregnancy and its functional withdrawal in reproductive tissue is linked with the onset of …

Mechanism of rhinovirus immunity and asthma

Z Yang, H Mitländer, T Vuorinen, S Finotto - Frontiers in immunology, 2021 - frontiersin.org
The majority of asthma exacerbations in children are caused by Rhinovirus (RV), a positive
sense single stranded RNA virus of the Picornavirus family. The host has developed virus …