Inflammation in anxiety

S Salim, G Chugh, M Asghar - Advances in protein chemistry and structural …, 2012 - Elsevier
The idea of the existence of an interaction between the immune system and the central
nervous system (CNS) has prompted extensive research interest into the subject of “ …

A new vision for therapeutic hypothermia in the era of targeted temperature management: a speculative synthesis

TC Jackson, PM Kochanek - Therapeutic hypothermia and …, 2019 - liebertpub.com
Three decades of animal studies have reproducibly shown that hypothermia is profoundly
cerebroprotective during or after a central nervous system (CNS) insult. The success of …

Effects of IgLON5 antibodies on neuronal cytoskeleton: a link between autoimmunity and neurodegeneration

J Landa, C Gaig, J Plagumà, A Saiz… - Annals of …, 2020 - Wiley Online Library
Anti‐IgLON5 disease is a neurological disorder characterized by autoantibodies against
IgLON5 and pathological evidence of neuronal‐specific tau accumulation. Here, we report …

Uman-type neurofilament light antibodies are effective reagents for the imaging of neurodegeneration

G Shaw, I Madorsky, Y Li, YS Wang… - Brain …, 2023 - academic.oup.com
Recent work shows that certain antibody-based assays for the neurofilament light chain
detect informative signals in the CSF and blood of human and animals affected by a variety …

Potential contribution of oxidative stress and inflammation to anxiety and hypertension

S Salim, M Asghar, M Taneja, I Hovatta, G Chugh… - Brain research, 2011 - Elsevier
Previously, we have published that pharmacological induction of oxidative stress causes
anxiety-like behavior in rats and also is associated with hypertension in these animals. Here …

IFN‐β rescues neurodegeneration by regulating mitochondrial fission via STAT5, PGAM5, and Drp1

E Tresse, L Riera‐Ponsati, E Jaberi, WQG Sew… - The EMBO …, 2021 - embopress.org
Mitochondrial homeostasis is essential for providing cellular energy, particularly in resource‐
demanding neurons, defects in which cause neurodegeneration, but the function of …

[HTML][HTML] Inactivation of brain Cofilin-1 by age, Alzheimer's disease and γ-secretase

E Barone, S Mosser, PC Fraering - … Acta (BBA)-Molecular Basis of Disease, 2014 - Elsevier
Rapid remodeling of the actin cytoskeleton in the pre-and/or post-synaptic compartments is
responsible for the regulation of neuronal plasticity, which is an important process for …

Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons

JC Belrose, YF Xie, LJ Gierszewski, JF MacDonald… - Molecular brain, 2012 - Springer
Background Glutathione (GSH) plays an important role in neuronal oxidant defence.
Depletion of cellular GSH is observed in neurodegenerative diseases and thereby …

Long-term culture of astrocytes attenuates the readily releasable pool of synaptic vesicles

H Kawano, S Katsurabayashi, Y Kakazu, Y Yamashita… - PloS one, 2012 - journals.plos.org
The astrocyte is a major glial cell type of the brain, and plays key roles in the formation,
maturation, stabilization and elimination of synapses. Thus, changes in astrocyte condition …

Establishment of Long-Term Primary Cortical Neuronal Cultures From Neonatal Opossum Monodelphis domestica

A Petrović, J Ban, I Tomljanović, M Pongrac… - Frontiers in Cellular …, 2021 - frontiersin.org
Primary dissociated neuronal cultures have become a standard model for studying central
nervous system (CNS) development. Such cultures are predominantly prepared from the …