Flow virometry: a powerful tool to functionally characterize viruses

R Lippé - Journal of virology, 2018 - Am Soc Microbiol
For several decades, flow cytometry has been a common approach to analyze cells and sort
them to near-purity. It enables one to probe inner cellular molecules, surface receptors, or …

Flow virometry as a tool to study viruses

JLR Zamora, HC Aguilar - Methods, 2018 - Elsevier
In the last few decades, flow cytometry has redefined the field of biology, exponentially
enhancing our understanding of cells, immunology, and microbiology. Flow cytometry …

Single-dose mucosal replicon-particle vaccine protects against lethal Nipah virus infection up to 3 days after vaccination

SR Welch, JR Spengler, SC Genzer… - Science …, 2023 - science.org
Nipah virus (NiV) causes a highly lethal disease in humans who present with acute
respiratory or neurological signs. No vaccines against NiV have been approved to date …

[HTML][HTML] A post-transcriptional feedback mechanism for noise suppression and fate stabilization

MMK Hansen, WY Wen, E Ingerman, BS Razooky… - Cell, 2018 - cell.com
Diverse biological systems utilize fluctuations (" noise") in gene expression to drive lineage-
commitment decisions. However, once a commitment is made, noise becomes detrimental to …

Flow cytometric analysis of nanoscale biological particles and organelles

H Lian, S He, C Chen, X Yan - Annual Review of Analytical …, 2019 - annualreviews.org
Analysis of nanoscale biological particles and organelles (BPOs) at the single-particle level
is fundamental to the in-depth study of biosciences. Flow cytometry is a versatile technique …

Crystal structure of the pre-fusion Nipah virus fusion glycoprotein reveals a novel hexamer-of-trimers assembly

K Xu, YP Chan, B Bradel-Tretheway… - PLoS …, 2015 - journals.plos.org
Nipah virus (NiV) is a paramyxovirus that infects host cells through the coordinated efforts of
two envelope glycoproteins. The G glycoprotein attaches to cell receptors, triggering the …

[HTML][HTML] High sensitivity detection and sorting of infectious human immunodeficiency virus (HIV-1) particles by flow virometry

MM Bonar, JC Tilton - Virology, 2017 - Elsevier
Detection of viruses by flow cytometry is complicated by their small size. Here, we
characterized the ability of a standard (FACSAria II) and a sub-micron flow cytometer (A50 …

Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation

JJW Wong, TA Young, J Zhang, S Liu, GP Leser… - Nature …, 2017 - nature.com
Nipah virus is an emergent paramyxovirus that causes deadly encephalitis and respiratory
infections in humans. Two glycoproteins coordinate the infection of host cells, an attachment …

Novel roles of the Nipah virus attachment glycoprotein and its mobility in early and late membrane fusion steps

V Ortega, JLR Zamora, IA Monreal, DT Hoffman… - MBio, 2022 - Am Soc Microbiol
The Paramyxoviridae family comprises important pathogens that include measles (MeV),
mumps, parainfluenza, and the emerging deadly zoonotic Nipah virus (NiV) and Hendra …

Nipah virus matrix protein influences fusogenicity and is essential for particle infectivity and stability

E Dietzel, L Kolesnikova, B Sawatsky, A Heiner… - Journal of …, 2016 - Am Soc Microbiol
Nipah virus (NiV) causes fatal encephalitic infections in humans. To characterize the role of
the matrix (M) protein in the viral life cycle, we generated a reverse genetics system based …