Bone substitutes: a review of their characteristics, clinical use, and perspectives for large bone defects management

G Fernandez de Grado, L Keller… - Journal of tissue …, 2018 - journals.sagepub.com
Bone replacement might have been practiced for centuries with various materials of natural
origin, but had rarely met success until the late 19th century. Nowadays, many different bone …

[HTML][HTML] Calcium phosphate cements: Optimization toward biodegradability

I Lodoso-Torrecilla, JJJP van den Beucken, JA Jansen - Acta biomaterialia, 2021 - Elsevier
Synthetic calcium phosphate (CaP) ceramics represent the most widely used biomaterials
for bone regenerative treatments due to their biological performance that is characterized by …

Role of pore size and morphology in musculo-skeletal tissue regeneration

RA Perez, G Mestres - Materials Science and Engineering: C, 2016 - Elsevier
Biomaterials in the form of scaffolds hold great promise in the regeneration of diseased
tissues. The scaffolds stimulate cellular adhesion, proliferation and differentiation. While the …

Calcium phosphate cements for bone substitution: chemistry, handling and mechanical properties

J Zhang, W Liu, V Schnitzler, F Tancret, JM Bouler - Acta biomaterialia, 2014 - Elsevier
Since their initial formulation in the 1980s, calcium phosphate cements (CPCs) have been
increasingly used as bone substitutes. This article provides an overview on the chemistry …

[HTML][HTML] Injectable bone cements: What benefits the combination of calcium phosphates and bioactive glasses could bring?

Ö Demir-Oğuz, AR Boccaccini, D Loca - Bioactive materials, 2023 - Elsevier
Out of the wide range of calcium phosphate (CaP) biomaterials, calcium phosphate bone
cements (CPCs) have attracted increased attention since their discovery in the 1980s due to …

Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: a review

S Bose, S Tarafder - Acta biomaterialia, 2012 - Elsevier
Calcium phosphates (CaPs) are the most widely used bone substitutes in bone tissue
engineering due to their compositional similarities to bone mineral and excellent …

Critical review: Injectability of calcium phosphate pastes and cements

R O'neill, HO McCarthy, EB Montufar, MP Ginebra… - Acta biomaterialia, 2017 - Elsevier
Calcium phosphate cements (CPC) have seen clinical success in many dental and
orthopaedic applications in recent years. The properties of CPC essential for clinical …

Calcium phosphate cements as drug delivery materials

MP Ginebra, C Canal, M Espanol, D Pastorino… - Advanced drug delivery …, 2012 - Elsevier
Calcium phosphate cements are used as synthetic bone grafts, with several advantages,
such as their osteoconductivity and injectability. Moreover, their low-temperature setting …

A review of calcium phosphate cements and acrylic bone cements as injectable materials for bone repair and implant fixation

AM Yousefi - Journal of Applied Biomaterials & Functional …, 2019 - journals.sagepub.com
Treatment of bone defects caused by trauma or disease is a major burden on human
healthcare systems. Although autologous bone grafts are considered as the gold standard …

[HTML][HTML] Biological and mechanical performance and degradation characteristics of calcium phosphate cements in large animals and humans

L Schröter, F Kaiser, S Stein, U Gbureck, A Ignatius - Acta Biomaterialia, 2020 - Elsevier
Calcium phosphate cements (CPCs) have been used to treat bone defects and support
bone regeneration because of their good biocompatibility and osteointegrative behavior …