In this review article the history of leishmaniasis is discussed regarding the origin of the
genus Leishmania in the Mesozoic era and its subsequent geographical distribution, initial …

“We have never had such a sophisticated arsenal of technologies for treating diseases, yet
the gap in health outcomes keep getting wider. This is unacceptable.” This claim was made …

The African trypanosome, Trypanosoma brucei, maintains an integral link between cell cycle
regulation and differentiation during its intricate life cycle. Whilst extensive changes in …

Abstract Glycogen Synthase Kinase-3 (GSK-3) is a serine/threonine kinase which is
ubiquitously expressed and is regarded as a regulator for various cellular events and …

New drugs are needed to treat toxoplasmosis. Toxoplasma gondii calcium-dependent
protein kinases (Tg CDPKs) are attractive targets because they are absent in mammals. We …

Human African trypanosomiasis (HAT) or 'sleeping sickness 'is a neglected tropical disease
caused by the parasite Trypanosoma brucei. Novel models for funding pharmaceutical …

Neglected tropical diseases (NTDs) refer to a group of infectious diseases, which though
treatable and/or preventable, remain a leading cause of morbidity and mortality among the …

Leishmania is a protozoan parasite of the trypanosomatid family, causing a wide range of
diseases with different clinical manifestations including cutaneous, mucocutaneous and …

African sleeping sickness is endemic in sub-Saharan Africa where the WHO estimates that
60 million people are at risk for the disease. Human African trypanosomiasis (HAT) is 100 …

1.1. Kinetoplastid Parasites as Pathogenic Parasites: Overview, Life Cycle, Relevance of
Life Stages to Health Over the past decade, neglected tropical diseases (NTDs) have seen a …