Vitamin D in autoimmunity: molecular mechanisms and therapeutic potential

W Dankers, EM Colin, JP Van Hamburg… - Frontiers in …, 2017 - frontiersin.org
Over the last three decades, it has become clear that the role of vitamin D goes beyond the
regulation of calcium homeostasis and bone health. An important extraskeletal effect of …

Micronutrients in autoimmune diseases: possible therapeutic benefits of zinc and vitamin D

I Wessels, L Rink - The Journal of nutritional biochemistry, 2020 - Elsevier
A functional immune system is essential for healthy life. This is achieved by the coordinate
activation and interaction of different immune cells. One should be aware that activation of …

Immunomodulatory effect of vitamin D and its potential role in the prevention and treatment of type 1 diabetes mellitus—A narrative review

K Rak, M Bronkowska - Molecules, 2018 - mdpi.com
Type 1 diabetes mellitus is a chronic autoimmune disease associated with degeneration of
pancreatic β-cells that results in an inability to produce insulin and the need for exogenous …

Vitamin D: Implications for ocular disease and therapeutic potential

RY Reins, AM McDermott - Experimental eye research, 2015 - Elsevier
Vitamin D is a multifunctional hormone that is now known to play a significant role in a
variety of biological functions in addition to its traditional role in regulating calcium …

Vitamin D and regulation of vascular cell function

N Jamali, CM Sorenson… - American Journal of …, 2018 - journals.physiology.org
Vitamin D deficiency is linked to pathogenesis of many diseases including cardiovascular,
cancer, and various eye diseases. In recent years, important roles for vitamin D in regulation …

Role of neuroendocrine and neuroimmune mechanisms in chronic inflammatory rheumatic diseases—the 10-year update

RH Straub, JWJ Bijlsma, A Masi, M Cutolo - Seminars in arthritis and …, 2013 - Elsevier
Background Neuroendocrine immunology in musculoskeletal diseases is an emerging
scientific field. It deals with the aspects of efferent neuronal and neurohormonal bearing on …

Vitamin D, inflammation, and colorectal cancer progression: a review of mechanistic studies and future directions for epidemiological studies

AS van Harten-Gerritsen, MGJ Balvers… - … Biomarkers & Prevention, 2015 - AACR
Survival from colorectal cancer is positively associated with vitamin D status. However,
whether this association is causal remains unclear. Inflammatory processes may link vitamin …

Vitamin D receptor (VDR) gene polymorphism and risk of rheumatoid arthritis (RA): systematic review and meta-analysis

Z Bagheri-Hosseinabadi, D Imani, H Yousefi… - Clinical …, 2020 - Springer
Vitamin D is involved in immune system modulation as well as in calcium and bone
homeostasis, hence plays a role in rheumatoid arthritis (RA) etiopathogenesis. A bulk of …

Vitamin D reduces the differentiation and expansion of Th17 cells in young asthmatic children

A Hamzaoui, A Berraïes, B Hamdi, W Kaabachi… - Immunobiology, 2014 - Elsevier
Abstract Vitamin D [25 (OH) D3] deficiency has been associated with asthma as in many
inflammatory and autoimmune pathologies; however, there is still a lack of data about the …

Activation of the aryl hydrocarbon receptor affects activation and function of human monocyte-derived dendritic cells

C Wang, Z Ye, A Kijlstra, Y Zhou… - Clinical & Experimental …, 2014 - academic.oup.com
Aryl hydrocarbon receptor (AhR) is well known for mediating the toxic effects of dioxin-
containing pollutants, but has also been shown to be involved in the natural regulation of the …