The effects of reserpine on depression: A systematic review

R Strawbridge, RR Javed, J Cave… - Journal of …, 2023 - journals.sagepub.com
Background: Reserpine is an effective antihypertensive drug, but its role in routine practice
has declined such that it is rarely used. This is largely based on the assumption that …

[HTML][HTML] Depression in sub-saharan Africa

IT Gbadamosi, IT Henneh, OM Aluko… - IBRO neuroscience …, 2022 - Elsevier
Mood disorders can be considered among the most common and debilitating mental
disorders. Major depression, as an example of mood disorders, is known to severely reduce …

Thymol ameliorated neurotoxicity and cognitive deterioration in a thioacetamide-induced hepatic encephalopathy rat model; involvement of the BDNF/CREB signaling …

HA Ogaly, RF Abdel-Rahman, MAE Mohamed… - Food & Function, 2022 - pubs.rsc.org
In the present study, we aimed to delineate the neuroprotective potential of thymol (THY)
against neurotoxicity and cognitive deterioration induced by thioacetamide (TAA) in an …

Tailoring efficient fluorogenic tactic for ultrasensitive detection of dopamine in urine and rat brain through real-time and in situ formation of high-performance …

ZY Xu, XD He, HQ Luo, LQ Xu, NB Li - Analytical Chemistry, 2023 - ACS Publications
Owing to the predominance of dopamine (DA) in controlling mental health, planning an
innovative method for DA detection with simplicity and high efficacy is conducive to the …

Repeated reserpine treatment induces depressive-like behaviors accompanied with hippocampal impairment and synapse deficit in mice

X Qian, Z Zhong, S Lu, Y Zhang - Brain Research, 2023 - Elsevier
Depression remains a significant public health concern, and current animal models of
depression are limited in their ability to accurately mimic human depression. However …

Cardamom oil ameliorates behavioral and neuropathological disorders in a rat model of depression induced by reserpine

AA Abdel-Rasoul, NA Saleh, EN Hosny… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Depression is a public health problem. Despite the
availability of treatment options, its prevalence is increasing. A high rate of treatment failure …

Comparing the effect of fluoxetine, escitalopram, and sertraline, on the level of BDNF and depression in preclinical and clinical studies: a systematic review

N Talaee, S Azadvar, S Khodadadi, N Abbasi… - European Journal of …, 2024 - Springer
Brain-derived neurotrophic factor (BDNF) dysfunction is one of the most important
mechanisms underlying depression. It seems that selective serotonin reuptake inhibitors …

Stem cells therapeutic effect in a reserpine-induced fibromyalgia rat model: A possible NLRP3 inflammasome modulation with neurogenesis promotion in the cerebral …

SA Mokhemer, MK Desouky, AK Abdelghany… - Life Sciences, 2023 - Elsevier
Fibromyalgia is a chronic pain syndrome with a multifactorial pathophysiology affecting 2–
8% of the population. Aims To investigate the therapeutic effects of bone marrow …

Cerebrolysin alleviates early brain injury after traumatic brain injury by inhibiting neuroinflammation and apoptosis via TLR signaling pathway

W Lu, Z Zhu, D Shi, X Li, J Luo, X Liao - Acta cirurgica brasileira, 2022 - SciELO Brasil
Purpose: Traumatic brain injury (TBI) is a major cause of death and disability. Cerebrolysin
(CBL) has been reported to be anti-inflammatory by reducing reactive oxygen species (ROS) …

Cerebrolysin potentiates the antidepressant effect of lithium in a rat model of depression

AO Abdelaty, EK Tharwat, AI Abdelrahman… - Journal of Psychiatric …, 2024 - Elsevier
Rationale Depression is the most prevalent psychiatric disorder worldwide. Although
numerous antidepressant treatments are available, there is a serious clinical concern due to …